期刊
ONCOIMMUNOLOGY
卷 1, 期 5, 页码 783-785出版社
LANDES BIOSCIENCE
DOI: 10.4161/onci.19735
关键词
IL-17A; tumor; lung; T-bet; T-regulatory cells
In a recent study we reported increased expression of IL-17A in the lung of patients with lung adenocarcinoma. Local blockade of IL-17A in the lung, in a model of lung cancer revealed enhanced anti-tumor immunity characterized by increased IFN gamma, a diminished T-regulatory cell number and reduced tumor growth.
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