期刊
ONCOIMMUNOLOGY
卷 1, 期 5, 页码 759-761出版社
TAYLOR & FRANCIS INC
DOI: 10.4161/onci.19680
关键词
regulatory T cells; CCL22; NK cells; macrophages; breast cancer; breast epithelial cells; tolerance
Regulatory T cells (Treg) have been reported of poor prognosis for overall survival in primary breast tumors (BT). As CCL22 plays a major role in Treg recruitment within primary BT we deciphered the mechanisms involved in the CCL22 production by breast epithelial tumor cells and propose herein the major role of their innate immune recognition in this production.
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