Long non-cocing RNAs involved in immuune responses

A large number of human RNA transcripts, which do not encode proteins are defined as non-coding RNAs (ncRNAs).These ncRNAs are divided into two classes of different lengths; short and long ncRNAs. MicroRNAs are a major class of short ncRNAs, 22 nucleotides in length that regulate gene expression at the post-transcriptional level. Long non-coding RNAs (IncRNAs) are more than 200 nucleotides in length and play roles in various biological pathways. In this review, we summarize the functions of IncRNAs which regulate immune responses.