期刊
FRONTIERS IN IMMUNOLOGY
卷 5, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2014.00573
关键词
long non-coding RNA (IncRNA); innate immune response; NEAT1; translational repression
类别
A large number of human RNA transcripts, which do not encode proteins are defined as non-coding RNAs (ncRNAs).These ncRNAs are divided into two classes of different lengths; short and long ncRNAs. MicroRNAs are a major class of short ncRNAs, 22 nucleotides in length that regulate gene expression at the post-transcriptional level. Long non-coding RNAs (IncRNAs) are more than 200 nucleotides in length and play roles in various biological pathways. In this review, we summarize the functions of IncRNAs which regulate immune responses.
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