期刊
CURRENT OSTEOPOROSIS REPORTS
卷 11, 期 2, 页码 136-146出版社
SPRINGER
DOI: 10.1007/s11914-013-0140-9
关键词
High-resolution peripheral quantitative computed tomography; Bone strength; Assessment; Bone microarchitecture; VolumetricBMD; Fracture; Age; Therapy; Finite element analysis
资金
- NIAMS NIH HHS [R01 AR060700] Funding Source: Medline
Bone structure is an integral determinant of bone strength. The availability of high resolution peripheral quantitative computed tomography (HR-pQCT) has made it possible to measure three-dimensional bone microarchitecture and volumetric bone mineral density in vivo, with accuracy previously unachievable and with relatively low-dose radiation. Recent studies using this novel imaging tool have increased our understanding of age-related changes and sex differences in bone microarchitecture, as well as the effect of different pharmacological therapies. One advantage of this novel tool is the use of finite element analysis modelling to non-invasively estimate bone strength and predict fractures using reconstructed three-dimensional images. In this paper, we describe the strengths and limitations of HR-pQCT and review the clinical studies using this tool.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据