期刊
OPTICA
卷 2, 期 2, 页码 177-185出版社
OPTICAL SOC AMER
DOI: 10.1364/OPTICA.2.000177
关键词
-
类别
资金
- Wellcome Trust [095927/A/11/Z, 095927/B/11/Z]
- Wellcome Trust [095927/B/11/Z] Funding Source: Wellcome Trust
Single-molecule switching (SMS) microscopy is a super-resolution method capable of producing images with resolutions far exceeding that of the classical diffraction limit. However, like all optical microscopes, SMS microscopes are sensitive to, and often limited by, specimen-induced aberrations. Adaptive optics (AO) has proven beneficial in a range of microscopes to overcome the limitations caused by aberrations. We report here on new AO methods for SMS microscopy that enable the feedback correction of specimeninduced aberrations. The benefits are demonstrated through two-dimensional and three-dimensional STORM imaging. We expect that this advance will broaden the scope of SMS microscopy by enabling deep-cell and tissue-level imaging. (C) 2015 Optical Society of America
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据