Antimycobacterial potentials of quercetin and rutin against Mycobacterium tuberculosis H37Rv

Quercetin and rutin, two flavonoids were examined for antimycobacterial activities against M. tuberculosis H37Rv (ATCC 27294). The quercetin exhibited (99.30 +/- 0.268%) in (LRP) assay at 200 mu g/ml and 56.21 +/- 0.97% inhibition in (BMD) at 50 mu g/ml, whereas rutin exhibited (90.40 +/- 0.68%) in LRP assay at 200 mu g/ml and 56.10 +/- 0.67% inhibition in BMD at 50 mu g/ml. The minimum inhibitory concentration (MIC) was found to be 6.25 mu g ml(-1) and 25 mu g ml(-1) respectively. The current investigation suggests that quercetin has better inhibitory activity than rutin.