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Fernando D. Camargo et al.
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Bin Zhao et al.
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Matthias Lauth et al.
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Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon
Michael Overholtzer et al.
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Lars Zender et al.
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J Svärd et al.
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R Jesnowski et al.
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H Kimura et al.
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R Nusse
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Small molecule modulation of Smoothened activity
JK Chen et al.
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Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
J Taipale et al.
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