Monodisperse functional microspheres from step-growth click polymerizations: preparation, functionalization and implementation

Herein, we demonstrate that, monodisperse, cross-linked clickable microspheres are made via step-growth thiol-acrylate Michael addition polymerization. The diameter of the microsphere is varied from 1-10 mu m, depending on the cross-link density and the reaction conditions. Implementations of these microspheres including functionalized microspheres for click chemistry, polymeric composites, fluorescent labeling and polymer degradation are discussed and/or demonstrated.