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BIOINFORMATICS (2014)
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Cristina Bosch Calero et al.
CHANNELS (2014)
Conserved Single Residue in the BK Potassium Channel Required for Activation by Alcohol and Intoxication in C. elegans
Scott J. Davis et al.
JOURNAL OF NEUROSCIENCE (2014)
BK channel activation by tungstate requires the β1 subunit extracellular loop residues essential to modulate voltage sensor function and channel gating
Ana I. Fernandez-Marino et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2014)
Arachidonic acid activation of BKCa (Slo1) channels associated to the β1-subunit in human vascular smooth muscle cells
Pedro Martin et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2014)
An alcohol-sensing site in the calcium- and voltage-gated, large conductance potassium (BK) channel
Anna N. Bukiya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Recombinant Expression and Functional Characterization of Martentoxin: A Selective Inhibitor for BK Channel (α + β4)
Jie Tao et al.
TOXINS (2014)
DiBAC4(3) hits a sweet spot for the activation of arterial large-conductance Ca2+-activated potassium channels independently of the β1-subunit
Fabiana S. Scornik et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2013)
A BK (Slo1) channel journey from molecule to physiology
Gustavo F. Contreras et al.
CHANNELS (2013)
Positions of beta 2 and beta 3 subunits in the large-conductance calcium- and voltage-activated BK potassium channel
Roland S. Wu et al.
JOURNAL OF GENERAL PHYSIOLOGY (2013)
A point mutation in the human Slo1 channel that impairs its sensitivity to omega-3 docosahexaenoic acid
Toshinori Hoshi et al.
JOURNAL OF GENERAL PHYSIOLOGY (2013)
Mechanism of the modulation of BK potassium channel complexes with different auxiliary subunit compositions by the omega-3 fatty acid DHA
Toshinori Hoshi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Omega-3 fatty acids lower blood pressure by directly activating large-conductance Ca2+-dependent K+channels
Toshinori Hoshi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K+ channel
Anirban Banerjee et al.
ELIFE (2013)
BK channel beta 1 and beta 4 auxiliary subunits exert opposite influences on escalated ethanol drinking in dependent mice
Max Kreifeldt et al.
FRONTIERS IN INTEGRATIVE NEUROSCIENCE (2013)
Cerebrovascular Dilation via Selective Targeting of the Cholane Steroid-Recognition Site in the BK Channel β1-Subunit by a Novel Nonsteroidal Agent
Anna N. Bukiya et al.
MOLECULAR PHARMACOLOGY (2013)
Complex effects of 17β-estradiol on mitochondrial function
Anika Thiede et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2012)
Tungstate activates BK channels in a β subunit- and Mg2+-dependent manner: relevance for arterial vasodilatation
Ana I. Fernandez-Marino et al.
CARDIOVASCULAR RESEARCH (2012)
Calcium- and Voltage-Gated Potassium (BK) Channel Activators in the 5β-Cholanic Acid-3α-ol Analogue Series with Modifications in the Lateral Chain
Anna N. Bukiya et al.
CHEMMEDCHEM (2012)
Conformational coupling in BK potassium channels
Frank T. Horrigan
JOURNAL OF GENERAL PHYSIOLOGY (2012)
Modulation of BK channel voltage gating by different auxiliary β subunits
Gustavo F. Contreras et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
K+ Channels: Function-Structural Overview
Carlos Gonzalez et al.
COMPREHENSIVE PHYSIOLOGY (2012)
Enhancement Effects of Martentoxin on Glioma BK Channel and BK Channel (α+β1) Subtypes
Jie Tao et al.
PLOS ONE (2011)
The steroid interaction site in transmembrane domain 2 of the large conductance, voltage- and calcium-gated potassium (BK) channel accessory β1 subunit
Anna N. Bukiya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The Potential of Tetrandrine Against Gliomas
Yun Chen et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2010)
Location of modulatory β subunits in BK potassium channels
Guoxia Liu et al.
JOURNAL OF GENERAL PHYSIOLOGY (2010)
Novel Spliced Variants of Large-Conductance Ca2+-Activated K+-Channel β2-Subunit in Human and Rodent Pancreas
Susumu Ohya et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2010)
Allosteric interactions and the modular nature of the voltage- and Ca2+-activated (BK) channel
Ramon Latorre et al.
JOURNAL OF PHYSIOLOGY-LONDON (2010)
The BK potassium channel in the vascular smooth muscle and kidney: α- and β-subunits
Roland S. Wu et al.
KIDNEY INTERNATIONAL (2010)
Effects of docosahexaenoic acid on large-conductance Ca2+-activated K+ channels and voltage-dependent K+ channels in rat coronary artery smooth muscle cells
Li-hong Lai et al.
ACTA PHARMACOLOGICA SINICA (2009)
A large-conductance (BK) potassium channel subtype affects both growth and mineralization of human osteoblasts
Neil C. Henney et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2009)
Channel β2-4 subunits fail to substitute for β1 in sensitizing BK channels to lithocholate
Anna N. Bukiya et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Location of the β4 Transmembrane Helices in the BK Potassium Channel
Roland S. Wu et al.
JOURNAL OF NEUROSCIENCE (2009)
Identification of Large Conductance Calcium Activated Potassium Channel Accessory β4 Subunit in Rat and Mouse Bladder Smooth Muscle
Muyan Chen et al.
JOURNAL OF UROLOGY (2009)
BK Channels: mediators and models for alcohol tolerance
Steven N. Treistman et al.
TRENDS IN NEUROSCIENCES (2009)
BK channel subunit composition modulates molecular tolerance to ethanol
Paula L. Feinberg-Zadek et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2008)
Inhibition of martentoxin on neuronal BK channel subtype (α+β4):: Implications for a novel interaction model
Jian Shi et al.
BIOPHYSICAL JOURNAL (2008)
Structural basis for toxin resistance of β4-associated calcium-activated potassium (BK) channels
Geliang Gan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Species-specific differences among KCNMB3 BK β3 auxiliary subunits:: Some β3 N-terminal variants may be primate-specific subunits
Xuhui Zeng et al.
JOURNAL OF GENERAL PHYSIOLOGY (2008)
Modulation of hSlo BK current inactivation by fatty acid esters of CoA
Xiaolu Sun et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Identification of a BK channel auxiliary protein controlling molecular and behavioral tolerance to alcohol
Gilles E. Martin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
A marriage of convenience:: β-subunits and voltage-dependent K+ channels
Yolima P. Torres et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Modes of operation of the BKCa channel β2 subunit
Nicoletta Savalli et al.
JOURNAL OF GENERAL PHYSIOLOGY (2007)
Beta-subunits are important modulators of the acute response to alcohol in human BK channels
Paula L. Feinberg-Zadek et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2007)
Voltage-sensitive oxonol dyes are novel large-conductance Ca2+-activated K+ channel activators selective for β1 and β4 but not for β2 Subunits
Takashi Morimoto et al.
MOLECULAR PHARMACOLOGY (2007)
beta-subunit-dependent modulation of hSlo BK current by arachidonic acid
X. Sun et al.
JOURNAL OF NEUROPHYSIOLOGY (2007)
Modulation of the BK channel by estrogens: examination at single channel level
Heidi De Wet et al.
MOLECULAR MEMBRANE BIOLOGY (2006)
β2 and β4 subunits of BK channels confer differential sensitivity to acute modulation by steroid hormones
JT King et al.
JOURNAL OF NEUROPHYSIOLOGY (2006)
Mechanism of β4 subunit modulation of BK channels
B Wang et al.
JOURNAL OF GENERAL PHYSIOLOGY (2006)
Role of charged residues in the S1-S4 voltage sensor of BK channels
ZM Ma et al.
JOURNAL OF GENERAL PHYSIOLOGY (2006)
Calcium-activated potassium channels and the regulation of vascular tone
J Ledoux et al.
PHYSIOLOGY (2006)
Cardioprotective effects of estradiol include the activation of large-conductance Ca2+-activated K+ channels in cardiac mitochondria
S Ohya et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)
Estrogen regulates β1-subunit expression in Ca2+-activated K+ channels in arteries from reproductive tissues
D Nagar et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)
Gating and ionic currents reveal how the BKCa channel's Ca2+ sensitivity is enhanced by its β1 subunit
L Bao et al.
JOURNAL OF GENERAL PHYSIOLOGY (2005)
17-β-estradiol activates maxi-K channels through a non-genomic pathway in human breast cancer cells
G Coiret et al.
FEBS LETTERS (2005)
Differential effects of β1 and β2 subunits on BK channel activity
P Orio et al.
JOURNAL OF GENERAL PHYSIOLOGY (2005)
Effects of unsaturated fatty acids on calcium-activated potassium current in gastric myocytes of guinea pigs
Hai-Feng Zheng et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2005)
The solution structure of BmTx3B, a member of the scorpion toxin subfamily α-KTx 16
YF Wang et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2005)
Functional effects of auxiliary β4-subunit on rat large-conductance Ca2+-activated K+ channel
TS Ha et al.
BIOPHYSICAL JOURNAL (2004)
MUSCLE: multiple sequence alignment with high accuracy and high throughput
RC Edgar
NUCLEIC ACIDS RESEARCH (2004)
Estradiol binding to maxi-K channels induces their down-regulation via proteasomal degradation
VP Korovkina et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Genomic and non-genomic effects of estrogens on endothelial cells
T Simoncini et al.
STEROIDS (2004)
Somatic localization of a specific large-conductance calcium-activated potassium channel subtype controls compartmentalized ethanol sensitivity in the nucleus accumbens
G Martin et al.
JOURNAL OF NEUROSCIENCE (2004)
Interaction of agitoxin2, charybdotoxin, and iberiotoxin with potassium channels: Selectivity between voltage-gated and Maxi-K channels
YD Gao et al.
PROTEINS-STRUCTURE FUNCTION AND GENETICS (2003)
Ethanol sensitivity of BKCa channels from arterial smooth muscle does not require the presence of the β1-subunit
AM Dopico
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Site of action of fatty acids and other charged lipids on BKCa channels from arterial smooth muscle cells
AL Clarke et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Inactivation of BK channels by the NH2 terminus of the β2 auxiliary subunit:: An essential role of a terminal peptide segment of three hydrophobic residues
XM Xia et al.
JOURNAL OF GENERAL PHYSIOLOGY (2003)
Martentoxin, a novel K+ channel-blocking peptide: purification, cDNA and genomic cloning, and electrophysiological and pharmacological characterization
YH Ji et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Modulation of BKCa channel activity by fatty acids:: structural requirements and mechanism of action
AL Clarke et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2002)
New disguises for an old channel:: MaxiK channel β-subunits
P Orio et al.
NEWS IN PHYSIOLOGICAL SCIENCES (2002)
Integrated channel plasticity contributes to alcohol tolerance in neurohypophysial terminals
TK Knott et al.
MOLECULAR PHARMACOLOGY (2002)
17β-estradiol upregulates distinct maxi-K channel transcripts in mouse uterus
AJ Holdiman et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2002)
Ethylbromide tamoxifen, a membrane-impermeant antiestrogen, activates smooth muscle calcium-activated large-conductance potassium channels from the extracellular side
GM Dick et al.
MOLECULAR PHARMACOLOGY (2002)
(Xeno)estrogen sensitivity of smooth muscle BK channels conferred by the regulatory β1 subunit -: A study of β1 knockout mice
GM Dick et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Ethanol reduces excitability in a subgroup of primary sensory neurons by activation of BKCa channels
M Gruss et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
Slotoxin, αKTx1.11, a new scorpion peptide blocker of MaxiK channels that differentiates between α and α+β (β1 or β4) complexes
J Garcia-Valdes et al.
FEBS LETTERS (2001)
Tamoxifen activates smooth muscle BK channels through the regulatory β1 subunit
GM Dick et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels
VK Gribkoff et al.
NATURE MEDICINE (2001)
Regulation of BKca channels expressed in human embryonic kidney 293 cells by epoxyeicosatrienoic acid
M Fukao et al.
MOLECULAR PHARMACOLOGY (2001)
Vasoregulation by the β1 subunit of the calcium-activated potassium channel
R Brenner et al.
NATURE (2000)
Role of the β1 subunit in large-conductance Ca2+-activated K+ channel gating energetics -: Mechanisms of enhanced Ca2+ sensitivity
DH Cox et al.
JOURNAL OF GENERAL PHYSIOLOGY (2000)
Cloning and functional expression of two families of β-subunits of the large conductance calcium-activated K+ channel
VN Uebele et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Actions of epoxyeicosatrienoic acid on large-conductance Ca2+-activated K+ channels in pituitary GH3 cells
SN Wu et al.
BIOCHEMICAL PHARMACOLOGY (2000)
Functional coupling of the β1 subunit to the large conductance Ca2+-activated K+ channel in the absence of Ca2+ -: Increased Ca2+ sensitivity from a Ca2+-independent mechanism
CM Nimigean et al.
JOURNAL OF GENERAL PHYSIOLOGY (2000)
HKCNMB3 and hKCNMB4, cloning and characterization of two members of the large-conductance calcium-activated potassium channel β subunit family
R Behrens et al.
FEBS LETTERS (2000)
A neuronal β subunit (KCNMB4) makes the large conductance, voltage- and Ca2+-activated K+ channel resistant to chavybdotoxin and iberiotoxin
P Meera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Cloning and functional characterization of novel large conductance calcium-activated potassium channel β subunits, hKCNMB3 and hKCNMB4
R Brenner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)