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Modulation of myocardial contraction by peroxynitrite

期刊

FRONTIERS IN PHYSIOLOGY
卷 3, 期 -, 页码 -

出版社

FRONTIERS MEDIA SA
DOI: 10.3389/fphys.2012.00468

关键词

myocyte; peroxynitrite; nitric oxide synthase; Ca2+; cAMP-dependent protein kinase; protein phosphatase 2a

资金

  1. American Heart Association [0715159B]
  2. National Institutes of Health [K02HL094692, R01HL079283]
  3. [R01HL38324]
  4. [HL63744]
  5. [HL65608]

向作者/读者索取更多资源

Peroxynitri e is a potent oxidant that is quickly emerging as a crucial modulator of myocardial function. This review will focus on the regulation of myocardial contraction by peroxynitrite during health and disease, with a specific emphasis on cardiomyocyte Ca2+ handling, proposed signaling pathways, and protein end-targets.

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