4.5 Review

Calcium-permeable AMPA receptors in the retina

期刊

出版社

FRONTIERS MEDIA SA
DOI: 10.3389/fnmol.2011.00027

关键词

apoptosis; TARP; vision; polyamine; review; ganglion cell; receptor trafficking; feedback

资金

  1. NINDS Intramural Research Program
  2. NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [ZIANS003039] Funding Source: NIH RePORTER

向作者/读者索取更多资源

The retina transforms light entering the eye into a sophisticated neural representation of our visual world. Specialized synapses, cells, and circuits in the retina have evolved to encode luminance, contrast, motion, and other complex visual features. Although a great deal has been learned about the cellular morphology and circuitry that underlies this image processing, many of the synapses in the retina remain incompletely understood. For example, excitatory synapses in the retina feature the full panoply of glutamate receptors, but in most cases specific roles for different receptor subtypes are unclear. In this brief review, I will discuss recent progress toward understanding how Ca2+-permeable AMPA receptors (CP-GluARs) contribute to synaptic transmission and newly discovered forms of synaptic plasticity in the retina.

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