期刊
NUCLEUS
卷 3, 期 3, 页码 251-255出版社
TAYLOR & FRANCIS INC
DOI: 10.4161/nucl.20391
关键词
Rif1; silencing; SIRS; telomeres; chromosomes
类别
资金
- National Institutes of Health [GM51492, GM56890]
Many proteins are post-translationally modified by lipid moieties such as palmitoyl or prenyl (e. g., farnesyl) groups, creating functional proteolipids. Lipid modifications share the property of increasing a protein's hydrophobicity and thus the propensity of that protein to associate with a membrane. These modifications are used to control the localization and activity of membrane-associated proteins. A well-recognized paradigm is farnesylation of the Ras GTPase that helps target this critical signaling protein to the plasma membrane.(1)
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据