期刊
MEDICAL SCIENCE MONITOR
卷 19, 期 -, 页码 1195-1210出版社
INT SCIENTIFIC INFORMATION, INC
DOI: 10.12659/MSM.889815
关键词
inner ear disease; sensorineural hearing loss; tinnitus; vertigo; genetic therapy; stem cell therapy; Meniere's disease
In recent years, huge advances have taken place in understanding of inner ear pathophysiology causing sensorineural hearing loss, tinnitus, and vertigo. Advances in understanding comprise biochemical and physiological research of stimulus perception and conduction, inner ear homeostasis, and hereditary diseases with underlying genetics. This review describes and tabulates the various causes of inner ear disease and defines inner ear and non-inner ear causes of hearing loss, tinnitus, and vertigo. The aim of this review was to comprehensively breakdown this field of otorhinolaryngology for specialists and non-specialists and to discuss current therapeutic options in distinct diseases and promising research for future therapies, especially pharmaceutic, genetic, or stem cell therapy.
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