期刊
FRONTIERS IN IMMUNOLOGY
卷 6, 期 -, 页码 1-5出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2015.00227
关键词
aerobic glycolysis; non-malignant cells; cellular signalling; proliferation; immunometabolism
类别
资金
- Medical Research Council
- Barts and the London Charity
- Cancer Research UK
- Higher Education Funding Council for England
- Medical Research Council [1504990] Funding Source: researchfish
Aerobic glycolysis has been generally associated with cancer cell proliferation, but fascinating and novel data show that it is also coupled to a series of further cellular functions. In this Mini Review, we will discuss some recent findings to illustrate newly defined roles for this process, in particular in non-malignant cells, supporting the idea that metabolism can be considered as an integral part of cellular signaling. Consequently, metabolism should be regarded as a plastic and highly dynamic determinant of a wide range of cellular specific functions.
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