相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeutics
Timo Rath et al.
CRITICAL REVIEWS IN BIOTECHNOLOGY (2015)
Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A
Johnny Mahlangu et al.
BLOOD (2014)
The role of FcRn in antigen presentation
Kristi Baker et al.
FRONTIERS IN IMMUNOLOGY (2014)
Cross-presentation of IgG-containing immune complexes
Kristi Baker et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2013)
Neonatal Fc Receptor Expression in Dendritic Cells Mediates Protective Immunity against Colorectal Cancer
Kristi Baker et al.
IMMUNITY (2013)
The Immunologic Functions of the Neonatal Fc Receptor for IgG
Timo Rath et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2013)
Phase 3 Study of Recombinant Factor IX Fc Fusion Protein in Hemophilia B
Jerry S. Powell et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Transepithelial Transport of Fc-Targeted Nanoparticles by the Neonatal Fc Receptor for Oral Delivery
Eric M. Pridgen et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients
Amy D. Shapiro et al.
BLOOD (2012)
Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs
Jennifer A. Dumont et al.
BLOOD (2012)
Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients
Jerry S. Powell et al.
BLOOD (2012)
Pulmonary Administration of Interferon Beta-1a-Fc Fusion Protein in Non-Human Primates Using an Immunoglobulin Transport Pathway
Sebastien Vallee et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2012)
Neonatal Fc receptor for IgG (FcRn) expressed in the gastric epithelium regulates bacterial infection in mice
Y. Ben Suleiman et al.
MUCOSAL IMMUNOLOGY (2012)
The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies
Conglei Li et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Neonatal Fc Receptor Blockade by Fc Engineering Ameliorates Arthritis in a Murine Model
Dipesh A. Patel et al.
JOURNAL OF IMMUNOLOGY (2011)
A Neonatal Fc Receptor-Targeted Mucosal Vaccine Strategy Effectively Induces HIV-1 Antigen-Specific Immunity to Genital Infection
Li Lu et al.
JOURNAL OF VIROLOGY (2011)
Recent advances using FcRn overexpression in transgenic animals to overcome impediments of standard antibody technologies to improve the generation of specific antibodies
Imre Kacskovics et al.
MABS (2011)
Efficient mucosal vaccination mediated by the neonatal Fc receptor
Lilin Ye et al.
NATURE BIOTECHNOLOGY (2011)
Intracellular neutralization of viral infection in polarized epithelial cells by neonatal Fc receptor (FcRn)-mediated IgG transport
Yu Bai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells
Kristi Baker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Transfer of IgG in the female genital tract by MHC class I-related neonatal Fc receptor (FcRn) confers protective immunity to vaginal infection
Zili Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
THE ROLE OF SPECIFIC IgG AND COMPLEMENT IN COMBATING A PRIMARY MUCOSAL INFECTION OF THE GUT EPITHELIUM
C. Belzer et al.
EUROPEAN JOURNAL OF MICROBIOLOGY AND IMMUNOLOGY (2011)
Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy
Pingguo Chen et al.
BLOOD (2010)
Intracellular mechanisms of antigen cross presentation in dendritic cells
Sebastian Amigorena et al.
CURRENT OPINION IN IMMUNOLOGY (2010)
X-ray Crystal Structures of Monomeric and Dimeric Peptide Inhibitors in Complex with the Human Neonatal Fc Receptor, FcRn
Adam R. Mezo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Enhanced antibody half-life improves in vivo activity
Jonathan Zalevsky et al.
NATURE BIOTECHNOLOGY (2010)
The Versatile MHC Class I-related FcRn Protects IgG and Albumin from Degradation: Implications for Development of New Diagnostics and Therapeutics
Jan Terje Andersen et al.
DRUG METABOLISM AND PHARMACOKINETICS (2009)
An FcRn-Dependent Role for Anti-flagellin Immunoglobulin G in Pathogenesis of Colitis in Mice
Kanna Kobayashi et al.
GASTROENTEROLOGY (2009)
Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice
Hector Perez Montoyo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota
Yingzi Cong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn
Kristi Baker et al.
SEMINARS IN IMMUNOPATHOLOGY (2009)
Anti-inflammatory actions of intravenous immunoglobulin
Falk Nimmerjahn et al.
ANNUAL REVIEW OF IMMUNOLOGY (2008)
Reduction of IgG in nonhuman primates by a peptide antagonist of the neonatal Fc receptor FcRn
Adam R. Mezo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Infused Fc-tagged β-glucuronidase crosses the placenta and produces clearance of storage in utero in mucopolysaccharidosis VII mice
Jeffrey H. Grubb et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Podocytes use FcRn to clear IgG from the glomerular basement membrane
Shreeram Akilesh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Dependence of antibody-mediated presentation of antigen on FcRn
Shuo-Wang Qiao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism
Shreeram Akilesh et al.
JOURNAL OF IMMUNOLOGY (2007)
Amelioration of experimental autoimmune myasthenia gravis in rats by neonatal FcR blockade
Liming Liu et al.
JOURNAL OF IMMUNOLOGY (2007)
The antiinflammatory activity of IgG: the intravenous IgG paradox
Falk Nimmerjahn et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
FcRn: the neonatal Fc receptor comes of age
Derry C. Roopenian et al.
NATURE REVIEWS IMMUNOLOGY (2007)
Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease
Stefka B. Petkova et al.
INTERNATIONAL IMMUNOLOGY (2006)
Pulmonary administration of therapeutic proteins using an immunoglobulin transport pathway
Alan J. Bitonti et al.
ADVANCED DRUG DELIVERY REVIEWS (2006)
Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria
Masaru Yoshida et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Maternal antibodies enhance or prevent cytomegalovirus infection in the placenta by neonatal Fc receptor-mediated transcytosis
E Maidji et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Complete FcRn dependence for intravenous Ig therapy in autoimmune skin blistering diseases
N Li et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Delivery of an erythropoietin-Fc fusion protein by inhalation in humans through an immunoglobulin transport pathway
JA Dumont et al.
JOURNAL OF AEROSOL MEDICINE-DEPOSITION CLEARANCE AND EFFECTS IN THE LUNG (2005)
Refining the rules of gliadin T cell epitope binding to the disease-associated DQ2 molecule in celiac disease: Importance of proline spacing and glutamine deamidation
SW Qiao et al.
JOURNAL OF IMMUNOLOGY (2005)
Oral and pulmonary delivery of FSH-Fc fusion proteins via neonatal Fc receptor-mediated transcytosis
SC Low et al.
HUMAN REPRODUCTION (2005)
From sorting endosomes to exocytosis: Association of Rab4 and Rab11 GTPases with the fc receptor, FcRn, during recycling
ES Ward et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Bidirectional transepithelial IgG transport by a strongly polarized basolateral membrane Fcγ-receptor
SM Claypool et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Visualizing the site and dynamics of IgG salvage by the MHC class I-related receptor, FcRn
RJ Ober et al.
JOURNAL OF IMMUNOLOGY (2004)
Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway
AJ Bitonti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells
M Yoshida et al.
IMMUNITY (2004)
Critical role of T cell-dependent serum antibody, but not the gut-associated lymphoid tissue, for surviving acute mucosal infection with Citrobacter rodentium, an attaching and effacing pathogen
L Bry et al.
JOURNAL OF IMMUNOLOGY (2004)
The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs
DC Roopenian et al.
JOURNAL OF IMMUNOLOGY (2003)
Evidence to support the cellular mechanism involved in serum IgG homeostasis in humans
ES Ward et al.
INTERNATIONAL IMMUNOLOGY (2003)
Receptor-mediated immunoglobulin G transport across mucosal barriers in adult life: Functional expression of FcRn in the mammalian lung
GM Spiekermann et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Functional reconstitution of human FcRn in Madin-Darby canine kidney cells requires co-expressed human β2-microglobulin
SM Claypool et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Apical to basolateral transcytosis and apical recycling of immunoglobulin G in trophoblast-derived BeWo cells: Effects of low temperature, nocodazole, and cytochalasin D
I Ellinger et al.
EXPERIMENTAL CELL RESEARCH (2001)
MHC class I-related neonatal Fc receptor for IgG is functionally expressed in monocytes, intestinal macrophages, and dendritic cells
XP Zhu et al.
JOURNAL OF IMMUNOLOGY (2001)
Expression of functionally active FcRn and the differentiated bidirectional transport of IgG in human placental endothelial cells
F Antohe et al.
HUMAN IMMUNOLOGY (2001)
分享论文
