期刊
JOURNAL OF MATERIALS CHEMISTRY B
卷 2, 期 35, 页码 5718-5738出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4tb00881b
关键词
-
资金
- Canadian Institutes of Health Research
- Natural Sciences and Engineering Research Council of Canada
- National Natural Science Foundation of China [21204005, 21334004, 21304062]
- Natural Science Foundation of Jiangsu Province [13KJA430006, 13KJB430020]
- China Postdoctoral Science Foundation [2013M541714]
Devices that function in contact with blood are ubiquitous in clinical medicine and biotechnolOgy. These devices include vascular grafts, coronary stents, heart valves, catheters, hemodialysers, heart-lung bypass systems and many others. Blood contact generally leads to thrombosis (among other adverse outcomes), and no material has yet been developed which remains thrombus-free indefinitely and in all situations: extracorporeally, in the venous circulation and in the arterial circulation. In this article knowledge on blood material interactions and thromboresistant materials is reviewed. Current approaches to the development of thromboresistant materials are discussed including surface passivation; incorporation and/or release of anticoagulants, antiplatelet agents and thrombolytic agents; and mimicry of the vascular endothelium.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据