期刊
JOURNAL OF MATERIALS CHEMISTRY B
卷 2, 期 15, 页码 2093-2096出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3tb21801e
关键词
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资金
- 973 Program [2013CB127603]
- National Science Foundation of China [21174012, 51103008, 51221002, 31372255]
- Beijing Natural Science Foundation [2142026]
- Special Fund for Agro-scientific Research in the Public Interest [201003025]
- New Century Excellent Talents Award Program from the Ministry of Education of China [NCET-10-0215]
- Doctoral Program of Higher Education Research Fund [20120010110008]
Multifunctional dithioacetal-modified perylenediimide (DTPDI) is synthesized as a highly sensitive and selective fluorescent chemosensor for recyclable Hg2+ detection and an effective DNA carrier. The central PDI chromophore allows the tracing of cell uptake by fluorescence microscopy, dithioacetals enable the detection of Hg2+, and peripheral amine hydrochloride salts increase the water solubility and also serve as positive charges for noncovalent binding of negatively charged DNA. In addition to serve as a recyclable fluorescent probe for Hg2+ detection, DTPDI can be rapidly internalized into live cells with low cytotoxicity and high DNA delivery efficacy.
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