期刊
JOURNAL OF MATERIALS CHEMISTRY B
卷 2, 期 46, 页码 8085-8097出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4tb01141d
关键词
-
资金
- NIH [R01 EB006818, U01 EB016027]
- National Center for Advancing Translational Sciences of the National Institutes of Health [UL1 TR000003]
Polymer-based nanogel formulations offer features attractive for drug delivery, including ease of synthesis, controllable swelling and viscoelasticity as well as drug loading and release characteristics, passive and active targeting, and the ability to formulate nanogel carriers that can respond to biological stimuli. These unique features and low toxicity make the nanogels a favorable option for vascular drug targeting. In this review, we have addressed key chemical and biological aspects of nanogel drug carrier design. In particular, we have highlighted published studies of nanogel design, descriptions of nanogel functional characteristics and their behavior in biological models. These studies form a compendium of information that supports the scientific and clinical rationale for development of this carrier for targeted therapeutic interventions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据