期刊
JOURNAL OF MATERIALS CHEMISTRY B
卷 2, 期 48, 页码 8466-8478出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4tb01095g
关键词
-
资金
- Swedish Research Council, Sweden [2012-42315-94008-81]
Peptides that self-assemble into well-defined nanofibrous networks provide a prominent alternative to traditional biomaterials for fabricating scaffolds for use in regenerative medicine and other biomedical applications. Such scaffolds can be generated by decorating a peptide backbone with other bioactives such as cell specific adhesion peptides, growth factors and enzyme cleavable sequences. They can be designed to mimic the three-dimensional (3D) structural features of native ECM and can therefore also provide insight into the ECM-cell interactions needed for development of scaffolds that can serve as regeneration templates for specific target tissues or organs. This review highlights the potential application of self-assembling peptides in regenerative medicine.
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