期刊
JOURNAL OF MATERIALS CHEMISTRY B
卷 2, 期 27, 页码 4346-4355出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4tb00243a
关键词
-
资金
- Program for New Century Excellent Talents in University [NCET-10-0623]
- Specialized Research Fund for the Doctoral Program of Higher Education
- National Science Foundation of China [21076145]
- National Science Fund for Distinguished Young Scholars [21125627]
- Program of Introducing Talents of Discipline to Universities [B06006]
A mild and efficient method for the construction of robust organic-inorganic hybrid microcapsules was developed by merging of covalent cross-linking and biomimetic mineralization into a layer-by-layer (LBL) self-assembly process. The diatom cell-inspired microcapsule structure had a biocompatible inner organic layer which could create a suitable microenvironment for biologically active substances inside the microcapsules and an inorganic layer which could function as a supporting membrane to maintain the intact morphology of the microcapsules. When in 40% PSS solution, only 5% of the hybrid microcapsules were deformed indicating that the hybrid microcapsule had a higher mechanical stability. The combination of the advantages of both the organic layer and the inorganic layer was applied for the immobilization of catalase (CAT). After being reused 7 times, the CAT in the hybrid microcapsules retained 78% of its initial activity. A buffering effect was created by the capsule wall and the immobilized CAT had a higher pH stability than the free CAT. After storing for 45 days, the CAT in the hybrid microcapsules retained 78% of its initial activity. It is envisaged that the as-prepared hybrid microcapsules can be extended to many applications such as biocatalysis, drug/gene delivery and biosensor fields.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据