期刊
CURRENT OPINION IN INSECT SCIENCE
卷 11, 期 -, 页码 21-30出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.cois.2015.08.001
关键词
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资金
- Ministry of Education, Culture, Sports, Science and Technology of Japan
- Takeda Science Foundation
- JSPS
- Naito Foundation
- NIH from NICHD [R00 HD073239]
- Grants-in-Aid for Scientific Research [26650113] Funding Source: KAKEN
In metazoans, members of the insulin-like peptide (ILP) family play a role in multiple physiological functions in response to the nutritional status. ILPs have been identified and characterized in a wide variety of insect species. Insect ILPs that are mainly produced by several pairs of medial neurosecretory cells in the brain circulate in the hemolymph and act systemically on target tissues. Physiological and biochemical studies in Lepidoptera and genetic studies in the fruit fly have greatly expanded our knowledge of the physiological functions of ILPs. Here, we outline the recent progress of the structural classification of insect ILPs and overview recent studies that have elucidated the physiological functions of insect ILPs involved in nutrient-dependent growth during development.
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