期刊
JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY
卷 10, 期 5, 页码 -出版社
IMPERIAL COLLEGE PRESS
DOI: 10.1142/S0219720012710011
关键词
Bioinformatics; full human genome sequencing; gene function; protein function prediction; biomolecular mechanism
The contrast between the pomp of celebrating the first full human genome sequencing in 2000 and the cautious tone of recollections a decade thereafter could hardly be greater. The promises with regard to medical cures and biotechnology applications have been realized not even nearly to the expectations. Understanding the human genomes means knowing the genes' and proteins' functions and their interconnectedness via biomolecular mechanisms. This articles estimates how long will it take to achieve this goal if we extrapolate from the previous decade (indeed, a century!) and the possible disruptive trends in science, technology and society that may accelerate the pace of progress dramatically.
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