相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Processing of hemojuvelin requires retrograde trafficking to the Golgi in HepG2 cells
Julia E. Maxson et al.
BLOOD (2009)
Regulation of growth differentiation factor 15 expression by intracellular iron
Samira Lakhal et al.
BLOOD (2009)
Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness
Jaroslav Truksa et al.
BLOOD (2009)
Contribution of STAT3 and SMAD4 pathways to the regulation of hepcidin by opposing stimuli
Hua Huang et al.
BLOOD (2009)
The molecular basis of hepcidin-resistant hereditary hemochromatosis
Augustine Fernandes et al.
BLOOD (2009)
Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells
Toshihiko Tanno et al.
BLOOD (2009)
Growth differentiation factor 15 production is necessary for normal erythroid differentiation and is increased in refractory anaemia with ring-sideroblasts
Jean-Marie Ramirez et al.
BRITISH JOURNAL OF HAEMATOLOGY (2009)
Regulation of iron metabolism through GDF15 and hepcidin in pyruvate kinase deficiency
Armin Finkenstedt et al.
BRITISH JOURNAL OF HAEMATOLOGY (2009)
Intestinal Hypoxia-inducible Transcription Factors Are Essential for Iron Absorption following Iron Deficiency
Yatrik M. Shah et al.
CELL METABOLISM (2009)
Interaction of the Hereditary Hemochromatosis Protein HFE with Transferrin Receptor 2 Is Required for Transferrin-Induced Hepcidin Expression
Junwei Gao et al.
CELL METABOLISM (2009)
A Ferroportin Transcript that Lacks an Iron-Responsive Element Enables Duodenal and Erythroid Precursor Cells to Evade Translational Repression
De-Liang Zhang et al.
CELL METABOLISM (2009)
HIF-2α, but not HIF-1α, promotes iron absorption in mice
Maria Mastrogiannaki et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD
Guillem Casanovas et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2009)
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
Delphine Meynard et al.
NATURE GENETICS (2009)
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
Billy Andriopoulos et al.
NATURE GENETICS (2009)
Nramp1 promotes efficient macrophage recycling of iron following erythrophagocytosis in vivo
Shan Soe-Lin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2
Ivana De Domenico et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Elevated growth differentiation factor 15 expression in patients with congenital dyserythropoietic anemia type I
Hannah Tamary et al.
BLOOD (2008)
Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis
Alicia R. Folgueras et al.
BLOOD (2008)
Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin
Yin Xia et al.
BLOOD (2008)
Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver
Leon Kautz et al.
BLOOD (2008)
Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPα
Jorge P. Pinto et al.
BLOOD (2008)
Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site
Lan Lin et al.
BLOOD CELLS MOLECULES AND DISEASES (2008)
Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum
Bruno Galy et al.
CELL METABOLISM (2008)
被撤回的出版物: The hepcidin-binding site on ferroportin is evolutionarily conserved (Retracted article. See vol. 19, pg. 1067, 2014)
Ivana De Domenico et al.
CELL METABOLISM (2008)
The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression
Paul J. Schmidt et al.
CELL METABOLISM (2008)
The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin
Laura Silvestri et al.
CELL METABOLISM (2008)
A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron
Maria Antonietta Melis et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2008)
The hereditary hemochromatosis protein, HFE, inhibits iron uptake via down-regulation of Zip14 in HepG2 cells
Junwei Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Neogenin-mediated hemojuvelin shedding occurs after hemojuvelin traffics to the plasma membrane
An-Sheng Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Small-Molecule Inhibitors of HIF-2a Translation Link Its 5′UTR Iron-Responsive Element to Oxygen Sensing
Michael Zimmer et al.
MOLECULAR CELL (2008)
Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)
Karin E. Finberg et al.
NATURE GENETICS (2008)
The serine protease TMPRSS6 is required to sense iron deficiency
Xin Du et al.
SCIENCE (2008)
A heme export protein is required for red blood cell differentiation and iron homeostasis
Sioban B. Keel et al.
SCIENCE (2008)
HFE modulates transferrin receptor 2 levels in hepatoma cells via interactions that differ from transferrin receptor 1-HFE interactions
Juxing Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Different regulatory elements are required for response of hepcidin to interleukin-6 and bone morphogenetic proteins 4 and 9
Jaroslav Truksa et al.
BRITISH JOURNAL OF HAEMATOLOGY (2007)
Expression and localization of hepcidin in macrophages: a role in host defense against tuberculosis
Fatoumata B. Sow et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin
Toshihiko Tanno et al.
NATURE MEDICINE (2007)
Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs)
Carole Peyssonnaux et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance
Jodie L. Babitt et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Iron-regulatory proteins limit hypoxia-inducible factor-2α expression in iron deficiency
Mayka Sanchez et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin
An-Sheng Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Interleukin induces hepcidin expression through STAT3
Diedra M. Wrighting et al.
BLOOD (2006)
Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing
Tapasree Goswami et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Hepcidin expression and iron transport in alveolar macrophages
Ngoc-Bich Nguyen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2006)
TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens
C Peyssonnaux et al.
BLOOD (2006)
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
JL Babitt et al.
NATURE GENETICS (2006)
A role of SMAD4 in iron metabolism through the positive regulation of hepicidin expression
RH Wang et al.
CELL METABOLISM (2005)
Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells
AS Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload
V Niederkofler et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
A mouse model of juvenile hemochromatosis
FW Huang et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
E Nemeth et al.
SCIENCE (2004)
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
G Papanikolaou et al.
NATURE GENETICS (2004)
Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor
MJ Bennett et al.
NATURE (2000)
分享论文
