期刊
FRONTIERS IN PLANT SCIENCE
卷 2, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fpls.2011.00063
关键词
C-13-metabolic flux analysis; primary metabolism; flux balance analysis; carbon partitioning; constraint-based model
资金
- U.S. Department of Energy (Division of Chemical Sciences, Geosciences, and Biosciences, Office of Basic Energy Sciences) [BO-133]
Metabolic flux is a fundamental property of living organisms. In recent years, methods for measuring metabolic flux in plants on a network scale have evolved further. One major challenge in studying flux in plants is the complexity of the plant's metabolism. In particular, in the presence of parallel pathways in multiple cellular compartments, the core of plant central metabolism constitutes a complex network. Hence, a common problem with the reliability of the contemporary results of C-13-Metabolic Flux Analysis in plants is the substantial reduction in complexity that must be included in the simulated networks; this omission partly is due to limitations in computational simulations. Here, I discuss recent emerging strategies that will better address these shortcomings.
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