期刊
FRONTIERS IN MICROBIOLOGY
卷 4, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fmicb.2013.00096
关键词
antimicrobial resistance; human and veterinary medicine; environment; soil; wastewater; resistance genes
类别
资金
- COST
- FCT-Fundaylo para a Ciencia e a Tecnologia [PEst-OE/EQB/LA0016/2011, PTDC/AAC-AMB/113840/2009]
- Swiss Federal Office for Agriculture
- Swiss Federal Office for the Environment
- Swiss Expert Committee for Biosafety (SECB)
- Fundação para a Ciência e a Tecnologia [PTDC/AAC-AMB/113840/2009] Funding Source: FCT
one of the greatest medical triumphs of the 20th century that revolutionized the treatment of bacterial infections. However, the gradual emergence of populations of antimicrobial-resistant pathogenic bacteria resulting from use, misuse, and abuse of antimicrobials has today become a major global health concern. Antimicrobial resistance (AMR) genes have been suggested to originate from environmental bacteria, as clinically relevant resistance genes have been detected on the chromosome of environmental bacteria. As only a few new antimicrobials have been developed in the last decade, the further evolution of resistance poses a serious threat to public health. Urgent measures are required not only to minimize the use of antimicrobials for prophylactic and therapeutic purposes but also to look for alternative strategies for the control of bacterial infections. This review examines the global picture of antimicrobial resistance, factors that favor its spread, strategies, and limitations for its control and the need for continuous training of all stake holders i.e., medical, veterinary, public health, and other relevant professionals as well as human consumers, in the appropriate use of antimicrobial drugs.
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