相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Site-Specific Interaction between α-Synuclein and Membranes Probed by NMR-Observed Methionine Oxidation Rates
Alexander S. Maltsev et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Properties of native brain α-synuclein
Jacqueline Burre et al.
NATURE (2013)
Studying calcium-triggered vesicle fusion in a single vesicle-vesicle content and lipid-mixing system
Minjoung Kyoung et al.
NATURE PROTOCOLS (2013)
Large α-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking
Bong-Kyu Choi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Nigrostriatal overabundance of α-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity
Meret Nora Gaugler et al.
ACTA NEUROPATHOLOGICA (2012)
Impact of N-Terminal Acetylation of α-Synuclein on Its Random Coil and Lipid Binding Properties
Alexander S. Maltsev et al.
BIOCHEMISTRY (2012)
α-Synuclein in Central Nervous System and from Erythrocytes, Mammalian Cells, and Escherichia coli Exists Predominantly as Disordered Monomer
Bruno Fauvet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Systematic Mutagenesis of α-Synuclein Reveals Distinct Sequence Requirements for Physiological and Pathological Activities
Jacqueline Burre et al.
JOURNAL OF NEUROSCIENCE (2012)
A single vesicle-vesicle fusion assay for in vitro studies of SNAREs and accessory proteins
Jiajie Diao et al.
NATURE PROTOCOLS (2012)
Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons
Martin Lundblad et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion
Jiajie Diao et al.
ELIFE (2012)
Recent Advances in the Genetics of Parkinson's Disease
Ian Martin et al.
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 12 (2011)
α-Synuclein Populates Both Elongated and Broken Helix States on Small Unilamellar Vesicles
Sowmya Bekshe Lokappa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Functional Alterations to the Nigrostriatal System in Mice Lacking All Three Members of the Synuclein Family
Sabina Anwar et al.
JOURNAL OF NEUROSCIENCE (2011)
Parkinson's Disease and α-Synuclein Expression
Michael J. Devine et al.
MOVEMENT DISORDERS (2011)
A small pool of vesicles maintains synaptic activity in vivo
Annette Denker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
A soluble α-synuclein construct forms a dynamic tetramer
Wei Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release
Minjoung Kyoung et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Minglei Zhao et al.
PROTEIN SCIENCE (2011)
SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease
Pablo Garcia-Reitboeck et al.
BRAIN (2010)
A Pathologic Cascade Leading to Synaptic Dysfunction in α-Synuclein-Induced Neurodegeneration
David A. Scott et al.
JOURNAL OF NEUROSCIENCE (2010)
Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis
Venu M. Nemani et al.
NEURON (2010)
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
Jacqueline Burre et al.
SCIENCE (2010)
Multiple Tight Phospholipid-Binding Modes of α-Synuclein Revealed by Solution NMR Spectroscopy
Christina R. Bodner et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Interplay of α-synuclein binding and conformational switching probed by single-molecule fluorescence
Allan Chris M. Ferreon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both α-synuclein and γ-synuclein
Steven L. Senior et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
Complexin and Ca2+ stimulate SNARE-mediated membrane fusion
Tae-Young Yoon et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Structure of membrane-bound α-synuclein from site-directed spin labeling and computational refinement
Christine C. Jao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
α-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis
Kristin E. Larsen et al.
JOURNAL OF NEUROSCIENCE (2006)
Quantification of α-synuclein binding to lipid vesicles using fluorescence correlation spectroscopy
Elizabeth Rhoades et al.
BIOPHYSICAL JOURNAL (2006)
Locomotor hyperactivity and alterations in dopamine neurotransmission are associated with overexpression of A53T mutant human α-synuclein in mice
EL Unger et al.
NEUROBIOLOGY OF DISEASE (2006)
α-synuclein cooperates with CSPα in preventing neurodegeneration
S Chandra et al.
CELL (2005)
Protein production by auto-induction in high-density shaking cultures
FW Studier
PROTEIN EXPRESSION AND PURIFICATION (2005)
Structure and dynamics of micelle-bound human α-synuclein
TS Ulmer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia
JJ Zarranz et al.
ANNALS OF NEUROLOGY (2004)
α-synuclein locus duplication as a cause of familial Parkinson's disease
MC Chartier-Harlin et al.
LANCET (2004)
Role of α-synuclein in presynaptic dopamine recruitment
L Yavich et al.
JOURNAL OF NEUROSCIENCE (2004)
α-synuclein produces a long-lasting increase in neurotransmitter release
SM Liu et al.
EMBO JOURNAL (2004)
Double-knockout mice for α- and β-synucleins:: Effect on synaptic functions
S Chandra et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
α-synuclein locus triplication causes Parkinson's disease
AB Singleton et al.
SCIENCE (2003)
A structural and functional role for 11-mer repeats in α-synuclein and other exchangeable lipid binding proteins
R Bussell et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
A broken α-helix in folded α-synuclein
S Chandra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
M Bucciantini et al.
NATURE (2002)
Conformational properties of α-synuclein in its free and lipid-associated states
D Eliezer et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
α-synuclein membrane interactions and lipid specificity
EJ Jo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Fiber diffraction of synthetic α-synuclein filaments shows amyloid-like cross-β conformation
LC Serpell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
A Abeliovich et al.
NEURON (2000)