期刊
CRITICAL CARE NURSING CLINICS OF NORTH AMERICA
卷 24, 期 2, 页码 201-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ccell.2012.03.006
关键词
Wound healing; Stress; Cytokine; Cortisol; Psychoneuroimmunology; Oxytocin
类别
资金
- NCATS NIH HHS [UL1 TR000090] Funding Source: Medline
- NCCIH NIH HHS [R21 AT003912, AT003912] Funding Source: Medline
- NCI NIH HHS [P30 CA016058, CA16058, CA131029, CA126857, R01 CA126857, R01 CA131029] Funding Source: Medline
- NCRR NIH HHS [UL1RR025755, UL1 RR025755] Funding Source: Medline
- NIA NIH HHS [AG029562, P01 AG016321, R01 AG029562] Funding Source: Medline
- NIDCR NIH HHS [P50 DE013749] Funding Source: Medline
The Impact of Psychological Stress on Wound Healing: Methods and Mechanisms 201 Jean-Philippe Gouin and Janice K. Kiecolt-Glaser Converging and replicated evidence indicates that psychological stress can modulate wound-healing processes. This article reviews the methods and findings of experimental models of wound healing. Psychological stress can have a substantial and clinically relevant impact on wound repair. Physiologic stress responses can directly influence wound-healing processes. Furthermore, psychological stress can indirectly modulate the repair process by promoting the adoption of health-damaging behaviors. Translational work is needed to develop innovative treatments able to attenuate stress-induced delays in wound healing.
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