期刊
CHEMISTRYOPEN
卷 3, 期 1, 页码 19-22出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/open.201300042
关键词
arylation; heterocycles; hypervalent iodine; iodonium salts; oxidation
资金
- Swedish Research Council
- University of the Basque Country UPV/EHU [MOV09/23]
An efficient one-pot synthesis of N-heteroaryl iodonium triflates from the corresponding N-heteroaryl iodide and arene has been developed. The reaction conditions resemble our previous one-pot syntheses, with suitable modifications to allow N-heteroaryl groups. The reaction time is only 30min, and no anion exchange is required. The obtained iodonium salts were isolated in a protonated form, these salts can either be employed directly in applications or be deprotonated prior to use. The aryl groups were chosen to induce chemoselective transfer of the heteroaryl moiety to various nucleophiles. The reactivity and chemoselectivity of these iodonium salts were demonstrated by selectively introducing a pyridyl moiety onto both oxygen and carbon nucleophiles in good yields.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据