期刊
BIOMED RESEARCH INTERNATIONAL
卷 2014, 期 -, 页码 -出版社
HINDAWI LTD
DOI: 10.1155/2014/872370
关键词
-
资金
- Ministry of Science, Technology and Innovation, Government of Malaysia [01-02-04-009 BTK/ER/38]
The influenza virus (IV) is known to be a resistant virus with frequent mutations, causing severe respiratory diseases in the upper respiratory system. Public health concerns about clinical efficacy of all conventional drugs are ambiguous; therefore, finding additional therapeutic agents is critical to prevent and control influenza outbreaks. Influenza is associated with the induction of proinflammatory cytokines. Scientists have reported that anti- inflammatory drugs, with pleiotropic effects, reduce the burden of severe influenza diseases. Therefore, statins, which are cardioprotective drugs with anti- inflammatory and immunomodulatory effects, may help patients suffering from influenza virus (IV). This review delineates the potential use of statins as an alternative therapy in treating influenza related illness.
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