期刊
BIOMATERIALS SCIENCE
卷 1, 期 2, 页码 224-230出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2bm00114d
关键词
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资金
- University of Wollongong
- Centre of Excellence, Laureate
- Australian Research Council (ARC)
Drop-on-demand bioprinting allows the controlled placement of living cells, and will benefit research in the fields of tissue engineering, drug screening and toxicology. We show that a bio-ink based on a novel microgel suspension in a surfactant-containing tissue culture medium can be used to reproducibly print several different cell types, from two different commercially available drop-on-demand printing systems, over long printing periods. The bio-ink maintains a stable cell suspension, preventing the settling and aggregation of cells that usually impedes cell printing, whilst meeting the stringent fluid property requirements needed to enable printing even from many-nozzle commercial inkjet print heads. This innovation in printing technology may pave the way for the biofabrication of multi-cellular structures and functional tissue.
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