4.5 Article

Solid-supported DNA for asymmetric synthesis: a stepping-stone toward practical applications

期刊

BIOMATERIALS SCIENCE
卷 1, 期 10, 页码 1034-1036

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c3bm60134j

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资金

  1. Japan Science and Technology Corporation (JST)
  2. WPI program (iCeMS, Kyoto University)
  3. Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan
  4. Japan Society for the Promotion of Science (JSPS)

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We developed an affordable solid-supported DNA and demonstrated that it could be used as a reusable chiral source for the copper(II)-catalyzed Diels-Alder reaction in water. This study will be a valuable stepping-stone for the industrial application of DNA-based asymmetric synthesis.

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