期刊
ANNUAL REVIEW OF ANIMAL BIOSCIENCES, VOL 1
卷 1, 期 -, 页码 239-260出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev-animal-031412-103701
关键词
chicken; disease; genetic resistance; quantitative trait loci (QTLs); genomics; expression profiling
资金
- Biotechnology and Biological Sciences Research Council [BBS/E/D/20320000] Funding Source: Medline
- BBSRC [BBS/E/D/20320000] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BBS/E/D/20320000] Funding Source: researchfish
The chicken has led the way among agricultural animal species in infectious disease control and, in particular, selection for genetic resistance. The generation of the chicken genome sequence and the availability of other empowering tools and resources greatly enhance the ability to select for enhanced disease resistance via genetic markers and to understand more deeply the biological basis of host resistance. In this review, we discuss how integrated genomic approaches are able to identify specific genes and genetic markers associated with disease resistance, give select examples of contemporary work involving various genomic strategies to identify disease resistance genes, and finish by giving some final thoughts on predicted applications in the near future.
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