期刊
ADVANCES IN MATERIALS SCIENCE AND ENGINEERING
卷 2013, 期 -, 页码 -出版社
HINDAWI LTD
DOI: 10.1155/2013/169721
关键词
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资金
- Japan Society for the Promotion of Science [25630282]
- Institute of Ceramics Research and Education, NITech
- Grants-in-Aid for Scientific Research [25630282] Funding Source: KAKEN
In our earlier work, a cotton-like biodegradable composite, consisting of poly(l-lactic acid) with siloxane-containing vaterite, has been prepared by electrospinning. In the present work, the fibers skeleton of the cotton-like composites was modified successfully with imogolite, which is hydrophilic and biocompatible, via a dip process using ethanol diluted solution to improve the cellular initial attachment. Almost no change in the fiber morphology after the surface modification was observed. The surface-modified composite showed the similar calcium and silicate ions releasabilities, for activating the osteoblasts, as an unmodified one. Cell culture tests showed that the initial adhesion of murine osteoblast-like cells on the surface of the fibers was enhanced by surface modification.
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