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Xin Lin et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)
Affinity Maturation of Cry1Aa Toxin to the Bombyx mori Cadherin-Like Receptor by Directed Evolution
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Structure and Glycolipid Binding Properties of the Nematicidal Protein Cry5B
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Current models of the mode of action of Bacillus thuringiensis insecticidal crystal proteins: A critical review
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JOURNAL OF INVERTEBRATE PATHOLOGY (2012)
Molecular cloning, characterization, genomic organization and promoter analysis of the α1,6-fucosyltransferase gene (fut8) expressed in the rat hybridoma cell line YB2/0
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BMC BIOTECHNOLOGY (2011)
A Cry1Ac Toxin Variant Generated by Directed Evolution has Enhanced Toxicity against Lepidopteran Insects
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CURRENT MICROBIOLOGY (2011)
The Role of β20-β21 Loop Structure in Insecticidal Activity of Cry1Ac Toxin from Bacillus thuringiensis
Yuan Lv et al.
CURRENT MICROBIOLOGY (2011)
Bacillus thuringiensis: A story of a successful bioinsecticide
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Mortality Impact of Bt Transgenic Maize Roots Expressing eCry3.1Ab, mCry3A, and eCry3.1Ab Plus mCry3A on Western Corn Rootworm Larvae in the Field
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JOURNAL OF ECONOMIC ENTOMOLOGY (2011)
Participation of Valine 171 in α-Helix 5 of Bacillus thuringiensis Cry1Ab δ-Endotoxin in Translocation of Toxin into Lymantria dispar Midgut Membranes
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Lepidopteran-Active Variable-Region Sequence Imparts Coleopteran Activity in eCry3.1Ab, an Engineered Bacillus thuringiensis Hybrid Insecticidal Protein
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Role of Alkaline Phosphatase from Manduca sexta in the Mechanism of Action of Bacillus thuringiensis Cry1Ab Toxin
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JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Short-Term Evaluation in Growing Rats of Diet Containing Bacillus thuringiensis Cry1Ia12 Entomotoxin: Nutritional Responses and Some Safety Aspects
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JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2010)
Variant Cry1Ia toxins generated by DNA shuffling are active against sugarcane giant borer
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JOURNAL OF BIOTECHNOLOGY (2010)
Characterization of a Cry1Ac toxin-binding alkaline phosphatase in the midgut from Helicoverpa armigera (Hubner) larvae
Changming Ning et al.
JOURNAL OF INSECT PHYSIOLOGY (2010)
Analysis of Cry8Ka5-binding proteins from Anthonomus grandis (Coleoptera: Curculionidae) midgut
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JOURNAL OF INVERTEBRATE PATHOLOGY (2010)
Isoforms, Expression, Glycosylation, and Tissue Distribution of CTL2/SLC44A2
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Helix α4 of the Bacillus thuringiensis Cry1Aa Toxin Plays a Critical Role in the Postbinding Steps of Pore Formation
Frederic Girard et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2009)
Signaling versus punching hole: How do Bacillus thuringiensis toxins kill insect midgut cells?
M. Soberon et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
Domain II Loop 3 of Bacillus thuringiensis Cry1Ab Toxin Is Involved in a Ping Pong Binding Mechanism with Manduca sexta Aminopeptidase-N and Cadherin Receptors
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
N546 in beta 18-beta 19 loop is important for binding and toxicity of the Bacillus thuringiensis Cry1Ac toxin
Wang Fa Xiang et al.
JOURNAL OF INVERTEBRATE PATHOLOGY (2009)
Crystal structure of Bacillus thuringiensis Cry8Ea1: An insecticidal toxin toxic to underground pests, the larvae of Holotrichia parallela
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JOURNAL OF STRUCTURAL BIOLOGY (2009)
Dominant Negative Mutants of Bacillus thuringiensis Cry1Ab Toxin Function as Anti-Toxins: Demonstration of the Role of Oligomerization in Toxicity
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PLOS ONE (2009)
Strategies to improve the insecticidal activity of Cry toxins from Bacillus thuringiensis
L. Pardo-Lopez et al.
PEPTIDES (2009)
Cysteine scanning mutagenesis of α4, a putative pore-lining helix of the Bacillus thuringiensis insecticidal toxin Cry1Aa
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APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2008)
Investigating the properties of Bacillus thuringiensis cry proteins with novel loop replacements created using combinatorial molecular biology
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APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2008)
Location of the Bombyx mori 175 kDa cadherin-like protein-binding site on Bacillus thuringiensis Cry1Aa toxin
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FEBS JOURNAL (2008)
The pre-pore from Bacillus thuringiensis Cry1Ab toxin is necessary to induce insect death in Manduca sexta
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PEPTIDES (2008)
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TRENDS IN BIOTECHNOLOGY (2008)
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Bacillus thuringiensis Cry1Ab mutants affecting oligomer formation are non-toxic to Manduca sexta larvae
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Safety assessment of transgenic Bacillus thuringiensis with VIP insecticidal protein gene by feeding studies
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FOOD AND CHEMICAL TOXICOLOGY (2007)
Role of receptors in Bacillus thuringiensis crystal toxin activity
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MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2007)
A system for the directed evolution of the insecticidal protein from Bacillus thuringiensis
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MOLECULAR BIOTECHNOLOGY (2007)
Mode of action of Bacillus thuringiensis Cry and Cyt toxins and their potential for insect control
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TOXICON (2007)
A 90-day safety study of genetically modified rice expressing Cry1Ab protein (Bacillus thuringiensis toxin) in Wistar rats
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FOOD AND CHEMICAL TOXICOLOGY (2007)
Effects of disulfide bridges in domain I of Bacillus thuringiensis Cry1Aa δ-endotoxin on ion-channel formation in biological membranes
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BIOCHEMISTRY (2006)
Specific epitopes of domains II and III of Bacillus thuringiensis Cry1Ab toxin involved in the sequential interaction with cadherin and aminopeptidase-N receptors in Manduca sexta
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Cry toxin mode of action in susceptible and resistant Heliothis virescens larvae
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JOURNAL OF INVERTEBRATE PATHOLOGY (2006)
A mechanism of cell death involving an adenylyl cyclase/PKA signaling pathway is induced by the Cry1Ab toxin of Bacillus thuringiensis
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Functional display of Bacillus thuringiensis Cry1Ac toxin on T7 phage
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JOURNAL OF INVERTEBRATE PATHOLOGY (2006)
Crystal structure of the mosquito-iarvicidal toxin Cry4Ba and its biological implications
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JOURNAL OF MOLECULAR BIOLOGY (2005)
Oligomerization triggers binding of a Bacillus thuringiensis Cry1Ab pore-forming toxin to aminopeptidase N receptor leading to insertion into membrane microdomains
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BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2004)
Display of biologically functional insecticidal toxin on the surface of λ phage
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APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2004)
Helix 4 mutants of the Bacillus thuringiensis insecticidal toxin Cry1Aa display altered pore-forming abilities
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APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2004)
Molecular basis for Bacillus thuringiensis Cry1Ab toxin specificity:: Two structural determinants in the Manduca sexta Bt-R1 receptor interact with loops α-8 and 2 in domain II of Cy1Ab toxin
I Gómez et al.
BIOCHEMISTRY (2003)
Introduction of Culex toxicity into Bacillus thuringiensis Cry4Ba by protein engineering
MAF Abdullah et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2003)
Specific mutations within the α4-α5 loop of the Bacillus thuringiensis Cry4B toxin reveal a crucial role for Asn-166 and Tyr-170
Y Kanintronkul et al.
MOLECULAR BIOTECHNOLOGY (2003)
Hydropathic complementarity determines interaction of epitope 869HITDTNNK876 in Manduca sexta Bt-R1 receptor with loop 2 of domain II of Bacillus thuringiensis Cry1A toxins
I Gomez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Role of helix 3 in pore formation by the Bacillus thuringiensis insecticidal toxin Cry1Aa
V Vachon et al.
BIOCHEMISTRY (2002)
Role of Bacillus thuringiensis Cry1 δ endotoxin binding in determining potency during lepidopteran larval development
A Gilliland et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2002)
Cadherin-like receptor binding facilitates proteolytic cleavage of helix α-1 in domain I and oligomer pre-pore formation of Bacillus thuringiensis Cry1Ab toxin
I Gómez et al.
FEBS LETTERS (2002)
The α-helix 4 residue, Asn135, is involved in the oligomerization of Cry1Ac1 and Cry1Ab5 Bacillus thuringiensis toxins
NJ Tigue et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2001)
Crystallization of the Bacillus thuringiensis toxin Cry1Ac and its complex with the receptor ligand N-acetyl-D-galactosamine
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ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2001)
Bacillus thuringiensis delta-endotoxin Cry1 hybrid proteins with increased activity against the Colorado potato beetle
S Naimov et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2001)
Role of interdomain salt bridges in the pore-forming ability of the Bacillus thuringiensis toxins Cry1Aa and Cry1Ac
F Coux et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Structure of the insecticidal bacterial δ-endotoxin Cry3Bb1 of Bacillus thuringiensis
N Galitsky et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2001)
Structure of Cry2Aa suggests an unexpected receptor binding epitope
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CURRENT OPINION IN PLANT BIOLOGY (2001)
How Bacillus thuringiensis has evolved specific toxins to colonize the insect world
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TRENDS IN GENETICS (2001)
Structural and functional studies of α-helix 5 region from Bacillus thuringiensis Cry1Ab δ-endotoxin
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BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY (2001)
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