期刊
SILICON
卷 9, 期 4, 页码 495-501出版社
SPRINGER
DOI: 10.1007/s12633-014-9245-8
关键词
Aza-Michael addition reaction; Substituted N-phenylmaleimides; Substituted N-phenylsuccinimide possessing silatranes; Antimicrobial activity
资金
- UGC, New Delhi
An efficient method for C-N bond formation via aza-Michael addition of gamma-aminopropylsilatranes to substituted N-phenylmaleimides under mild conditions is described. The five receptors enclosing the maleimide moiety have been synthesized by the aza-Michael addition to strong nucleophile gamma-aminopropylsilatrane producing silatranes possessing substituted N-phenylsuccinimide at the axial position without any catalyst. All the compounds have been characterized by elemental analysis, spectro-scopic techniques and thermo-gravimetric analysis. The synthesized compounds have been screened for possible antimicrobial properties and results have shown modest activity.
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