期刊
PROTEIN & CELL
卷 4, 期 8, 页码 569-572出版社
HIGHER EDUCATION PRESS
DOI: 10.1007/s13238-013-3903-2
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资金
- NIH
- Ministry of Education of China
Ig superfamily (IgSF) constitutes the largest superfamily in human genome. In particular, Ig-like domains are the most abundant structural module within cell surface receptors, functioning in nervous as well as immune system. Here I describe some key sequence signature of an I-set Ig-like domain from known structures of IgSF members. These signature residues define the I-set Ig-like domain, which should aid structural and functional studies of cell surface receptors.
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