相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Lessons from interconnected ubiquitylation and acetylation of p53: think metastable networks
Monsef Benkirane et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2010)
SIRT1 Regulates UV-Induced DNA Repair through Deacetylating XPA
Wei Fan et al.
MOLECULAR CELL (2010)
Modes of p53 Regulation
Jan-Philipp Kruse et al.
CELL (2009)
Histone acetylation Where to go and how to get there
Vicki E. MacDonald et al.
EPIGENETICS (2009)
MSL2 Promotes Mdm2-independent Cytoplasmic Localization of p53
Jan-Philipp Kruse et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53
Dingding Shi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
Chunaram Choudhary et al.
SCIENCE (2009)
The first 30 years of p53: growing ever more complex
Arnold J. Levine et al.
NATURE REVIEWS CANCER (2009)
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
Rui-Hong Wang et al.
CANCER CELL (2008)
Acetylation is indispensable for p53 activation
Yi Tang et al.
CELL (2008)
Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation
Kai Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Negative regulation of the deacetylase SIRT1 by DBC1
Wenhui Zhao et al.
NATURE (2008)
DBC1 is a negative regulator of SIRT1
Ja-Eun Kim et al.
NATURE (2008)
Combinatorial patterns of histone acetylations and methylations in the human genome
Zhibin Wang et al.
NATURE GENETICS (2008)
SIRT1 Overexpression Antagonizes Cellular Senescence with Activated ERK/S6k1 Signaling in Human Diploid Fibroblasts
Jing Huang et al.
PLOS ONE (2008)
An acetylation switch in p53 mediates Holo-TFIID recruitment
Andrew G. Li et al.
MOLECULAR CELL (2007)
Targeted inactivation of mdm2 RING finger e3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation
Koji Itahana et al.
CANCER CELL (2007)
SIRT1 regulates the function of the nijmegen breakage syndrome protein
Zhigang Yuan et al.
MOLECULAR CELL (2007)
The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain
Hestia Mellert et al.
CELL CYCLE (2007)
ASPP: a new family of oncogenes and tumour suppressor genes
A. Sullivan et al.
BRITISH JOURNAL OF CANCER (2007)
Acetylation of the p53 DNA-binding domain regulates apoptosis induction
Stephen M. Sykes et al.
MOLECULAR CELL (2006)
Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis
Yi Tang et al.
MOLECULAR CELL (2006)
Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo
Ingo Ringshausen et al.
CANCER CELL (2006)
Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damage
Connie Chao et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey
Sung Chan Kim et al.
MOLECULAR CELL (2006)
Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate
Chad D. Knights et al.
JOURNAL OF CELL BIOLOGY (2006)
Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21Waf1/Cip1
Y Zhao et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
p53 ubiquitination: Mdm2 and beyond
CL Brooks et al.
MOLECULAR CELL (2006)
The C-terminal lysines fine-tune P53 stress responses in a mouse model but are not required for stability control or transactivation
KA Krummel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis
Q Zhong et al.
CELL (2005)
Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity
LJ Feng et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress
KF Chua et al.
CELL METABOLISM (2005)
ARF-BP1/mule is a critical mediator of the ARF tumor suppressor
DL Chen et al.
CELL (2005)
Calorie restriction, SIRT1 and metabolism: Understanding longevity
L Bordone et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Inhibition of p53 degradation by Mdm2 acetylation
XJ Wang et al.
FEBS LETTERS (2004)
Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo
JY Luo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Transcriptional regulatory code of a eukaryotic genome
CT Harbison et al.
NATURE (2004)
The ubiquitin ligase COP1 is a critical negative regulator of p53
D Dornan et al.
NATURE (2004)
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
HL Cheng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Identification and characterization of a novel p300-mediated p53 acetylation site, lysine 305
YH Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Polyubiquitination of p53 by a ubiquitin ligase activity of p300
SR Grossman et al.
SCIENCE (2003)
Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation
RP Leng et al.
CELL (2003)
Histone deacetylases (HDACs): characterization of the classical HDAC family
AJM De Ruijter et al.
BIOCHEMICAL JOURNAL (2003)
Acetylation of p53 inhibits its ubiquitination by Mdm2
MY Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
p53 mutant mice that display early ageing-associated phenotypes
SD Tyner et al.
NATURE (2002)
Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brcal1 BRCT structure
WS Joo et al.
GENES & DEVELOPMENT (2002)
Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases
NA Barlev et al.
MOLECULAR CELL (2001)
Negative control of p53 by Sir2α promotes cell survival under stress
JY Luo et al.
CELL (2001)
hSIR2SIRT1 functions as an NAD-dependent p53 deacetylase
H Vaziri et al.
CELL (2001)
The INK4a/ARF network in tumour suppression
CJ Sherr
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
Post-translational modifications and activation of p53 by genotoxic stresses
E Appella et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2001)
p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2
A Ito et al.
EMBO JOURNAL (2001)
Deacetylation of p53 modulates its effect on cell growth and apoptosis
JY Luo et al.
NATURE (2000)
Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation
MS Rodriguez et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
分享论文
