期刊
PROTEIN & CELL
卷 1, 期 6, 页码 520-536出版社
SPRINGEROPEN
DOI: 10.1007/s13238-010-0065-3
关键词
next-generation sequencing technology; RNA-seq; ChIP-seq; metagenome; transcriptome; epigenome
类别
资金
- Chinese Academy of Sciences Scientific Research Equipments [YZ200823]
- Institutional Director's Initiative Fund
As one of the key technologies in biomedical research, DNA sequencing has not only improved its productivity with an exponential growth rate but also been applied to new areas of application over the past few years. This is largely due to the advent of newer generations of sequencing platforms, offering ever-faster and cheaper ways to analyze sequences. In our previous review, we looked into technical characteristics of the next-generation sequencers and provided prospective insights into their future development. In this article, we present a brief overview of the advantages and shortcomings of key commercially available platforms with a focus on their suitability for a broad range of applications.
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