相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Structure-Function Analysis of STING Activation by c[G(2′,5′) pA(3′,5′)p] and Targeting by Antiviral DMXAA
Pu Gao et al.
CELL (2013)
Cyclic [G(2′,5′) pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
Pu Gao et al.
CELL (2013)
Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
Xu Zhang et al.
MOLECULAR CELL (2013)
cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
Andrea Ablasser et al.
NATURE (2013)
Structural mechanism of cytosolic DNA sensing by cGAS
Filiz Civril et al.
NATURE (2013)
Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
Jiaxi Wu et al.
SCIENCE (2013)
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
Lijun Sun et al.
SCIENCE (2013)
Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects
Xiao-Dong Li et al.
SCIENCE (2013)
Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity
Philip J. Kranzusch et al.
CELL REPORTS (2013)
The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
Elie J. Diner et al.
CELL REPORTS (2013)
The Amino Terminus of the Vaccinia Virus E3 Protein Is Necessary To Inhibit the Interferon Response
Stacy D. White et al.
JOURNAL OF VIROLOGY (2012)
Re(de)fining the dendritic cell lineage
Ansuman T. Satpathy et al.
NATURE IMMUNOLOGY (2012)
Innate Immune Response of Human Plasmacytoid Dendritic Cells to Poxvirus Infection Is Subverted by Vaccinia E3 via Its Z-DNA/RNA Binding Domain
Hua Cao et al.
PLOS ONE (2012)
MVA and NYVAC as Vaccines against Emergent Infectious Diseases and Cancer
Carmen E. Gomez et al.
CURRENT GENE THERAPY (2011)
Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses
Glen N. Barber
CURRENT OPINION IN IMMUNOLOGY (2011)
DDX1, DDX21, and DHX36 Helicases Form a Complex with the Adaptor Molecule TRIF to Sense dsRNA in Dendritic Cells
Zhiqiang Zhang et al.
IMMUNITY (2011)
Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
Taro Kawai et al.
IMMUNITY (2011)
The N-Ethyl-N-Nitrosourea-Induced Goldenticket Mouse Mutant Reveals an Essential Function of Sting in the In Vivo Interferon Response to Listeria monocytogenes and Cyclic Dinucleotides
John-Demian Sauer et al.
INFECTION AND IMMUNITY (2011)
Activation of Autophagy by α-Herpesviruses in Myeloid Cells Is Mediated by Cytoplasmic Viral DNA through a Mechanism Dependent on Stimulator of IFN Genes
Simon B. Rasmussen et al.
JOURNAL OF IMMUNOLOGY (2011)
Phase 1 Safety and Immunogenicity Testing of DNA and Recombinant Modified Vaccinia Ankara Vaccines Expressing HIV-1 Virus-like Particles
Paul A. Goepfert et al.
JOURNAL OF INFECTIOUS DISEASES (2011)
Myxoma Virus Induces Type I Interferon Production in Murine Plasmacytoid Dendritic Cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-Dependent Pathway
Peihong Dai et al.
JOURNAL OF VIROLOGY (2011)
STING is a direct innate immune sensor of cyclic di-GMP
Dara L. Burdette et al.
NATURE (2011)
The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells
Zhiqiang Zhang et al.
NATURE IMMUNOLOGY (2011)
Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pot and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1-uninfected volunteers: A phase I clinical trial (RISVAC02)
Felipe Garcia et al.
VACCINE (2011)
IFI16 is an innate immune sensor for intracellular DNA
Leonie Unterholzner et al.
NATURE IMMUNOLOGY (2010)
Vaccinia Virus-Mediated Inhibition of Type I Interferon Responses Is a Multifactorial Process Involving the Soluble Type I Interferon Receptor B18 and Intracellular Components
Zoe Waibler et al.
JOURNAL OF VIROLOGY (2009)
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
Hiroki Ishikawa et al.
NATURE (2009)
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
Wenxiang Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Modified vaccinia virus Ankara can activate NF-κB transcription factors through a double-stranded RNA-activated protein kinase (PKR)-dependent pathway during the early phase of virus replication
Heather E. Lynch et al.
VIROLOGY (2009)
The effect of the vaccinia K1 protein on the PKR-eIF2α pathway in RK13 and HeLa cells
Kristen L. Willis et al.
VIROLOGY (2009)
Innate Immune Sensing of Modified Vaccinia Virus Ankara (MVA) Is Mediated by TLR2-TLR6, MDA-5 and the NALP3 Inflammasome
Julie Delaloye et al.
PLOS PATHOGENS (2009)
Induction of IFN-β and the Innate Antiviral Response in Myeloid Cells Occurs through an IPS-1-Dependent Signal That Does Not Require IRF-3 and IRF-7
Stephane Daffis et al.
PLOS PATHOGENS (2009)
The poxvirus vectors MVA and NYVAC as gene delivery systems for vaccination against infectious diseases and cancer
Carmen E. Gomez et al.
CURRENT GENE THERAPY (2008)
The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
Bo Zhong et al.
IMMUNITY (2008)
Vaccinia Virus Subverts a Mitochondrial Antiviral Signaling Protein-Dependent Innate Immune Response in Keratinocytes through Its Double-Stranded RNA Binding Protein, E3
Liang Deng et al.
JOURNAL OF VIROLOGY (2008)
MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals
Lei Jin et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
Hiroki Ishikawa et al.
NATURE (2008)
Enhanced cell surface expression, immunogenicity and genetic stability resulting from a spontaneous truncation of HIV Env expressed by a recombinant MVA
Linda S. Wyatt et al.
VIROLOGY (2008)
Vaccinia virus proteins A52 and B14 share a Bcl-2-like fold but have evolved to inhibit NF-κB rather than apoptosis
Stephen C. Graham et al.
PLOS PATHOGENS (2008)
Vaccinia virus E3 protein prevents the antiviral action of ISG15
Susana Guerra et al.
PLOS PATHOGENS (2008)
The identification and characterization of a monoclonal antibody to the vaccinia virus E3 protein
Jessica R. Weaver et al.
VIRUS RESEARCH (2007)
Genomic sequence of chorioallantois vaccinia virus Ankara, the ancestor of modified vaccinia virus Ankara
Christine Meisinger-Henschel et al.
JOURNAL OF GENERAL VIROLOGY (2007)
Modified vaccinia virus Ankara induces toll-like receptor-independent type I interferon responses
Zoe Waibler et al.
JOURNAL OF VIROLOGY (2007)
Suppression of proinflammatory signal transduction and gene expression by the dual nucleic acid binding domains of the vaccinia virus EM proteins
Jeffrey O. Langland et al.
JOURNAL OF VIROLOGY (2006)
Vaccinia virus infection attenuates innate immune responses and antigen presentation by epidermal dendritic cells
Liang Deng et al.
JOURNAL OF VIROLOGY (2006)
Dynamic programing of CD8+ T cell trafficking after live viral immunization
Luzheng Liu et al.
IMMUNITY (2006)
Double-stranded RNA-binding protein E3 controls translation of viral intermediate RNA, marking an essential step in the life cycle of modified vaccinia virus Ankara
H Ludwig et al.
JOURNAL OF GENERAL VIROLOGY (2006)
Safety and immunogenicity of IMVAMUNE, a promising candidate as a third generation smallpox vaccine
J Vollmar et al.
VACCINE (2006)
Two-step Red-mediated recombination for versatile high-efficiency markerless DNA manipulation in Escherichia coli
BK Tischer et al.
BIOTECHNIQUES (2006)
Innate immune recognition of viral infection
T Kawai et al.
NATURE IMMUNOLOGY (2006)
Modified vaccinia virus Ankara protein F1L is a novel BH3-domain-binding protein and acts together with the early viral protein E3L to block virus-associated apoptosis
SF Fischer et al.
CELL DEATH AND DIFFERENTIATION (2006)
IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
Kenya Honda et al.
NATURE REVIEWS IMMUNOLOGY (2006)
Regulation of the type IIFN induction: a current view
K Honda et al.
INTERNATIONAL IMMUNOLOGY (2005)
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
T Kawai et al.
NATURE IMMUNOLOGY (2005)
The N-terminal domain of the vaccinia virus E3L-protein is required for neurovirulence, but not induction of a protective immune response
T Brandt et al.
VIROLOGY (2005)
Role of viral factor E3L in modified vaccinia virus Ankara infection of human HeLa cells: Regulation of the virus life cycle and identification of differentially expressed host genes
H Ludwig et al.
JOURNAL OF VIROLOGY (2005)
Poxvirus protein N1L targets the I-κB kinase complex, inhibits signaling to NF-κB by the tumor necrosis factor superfamily of receptors, and inhibits NF-κB and IRF3 signaling by Toll-like receptors
G DiPerna et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Modified vaccinia virus Ankara induces moderate activation of human dendritic cells
R Drillien et al.
JOURNAL OF GENERAL VIROLOGY (2004)
Modified vaccinia ankara: Potential as an alternative smallpox vaccine
LH McCurdy et al.
CLINICAL INFECTIOUS DISEASES (2004)
The poxvirus protein A52R targets toll-like receptor signaling complexes to suppress host defense
MT Harte et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
STAT3 is required for FIM-dependent dendritic cell differentiation
Y Laouar et al.
IMMUNITY (2003)
Inhibition of endosomal/lysosomal degradation increases the infectivity of human immunodeficiency virus
BL Fredericksen et al.
JOURNAL OF VIROLOGY (2002)
The vaccinia virus N1L protein is an intracellular homodimer that promotes virulence
N Bartlett et al.
JOURNAL OF GENERAL VIROLOGY (2002)
Blockade of interferon induction and action by the E3L double-stranded RNA binding proteins of vaccinia virus
Y Xiang et al.
JOURNAL OF VIROLOGY (2002)
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
L Alexopoulou et al.
NATURE (2001)
Role of hematopoietic growth factors/flt3 ligand in expansion and regulation of dendritic cells
HJ McKenna
CURRENT OPINION IN HEMATOLOGY (2001)
IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or IκB kinase but is blocked by vaccinia virus E3L protein
EJ Smith et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model
TA Brandt et al.
JOURNAL OF VIROLOGY (2001)
Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-α/β gene induction
M Sato et al.
IMMUNITY (2000)
A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling
A Bowie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
分享论文
