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Jorge R. Almeida et al.
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Apoptosis induced by the lymphocyte effector molecule perforin
Paul Bolitho et al.
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Perforin-mediated target-cell death and immune homeostasis
Ilia Voskoboinik et al.
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Cutting edge:: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation
Naofumi Takemoto et al.
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George Makedonas et al.
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Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry
Pratip K. Chattopadhyay et al.
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Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases
G Pantaleo et al.
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Functional signatures of protective antiviral T-cell immunity in human virus infections
Alexandre Harari et al.
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Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
AM Intlekofer et al.
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IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508
ES Hwang et al.
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Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects
AW Sylwester et al.
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HIV-1-specific IFN-γ/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells
SC Zimmerli et al.
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Conserved CTL epitopes on the adenovirus hexon protein expand subgroup cross-reactive and subgroup-specific CD8+ T cells
AM Leen et al.
BLOOD (2004)
Antigen-driven effector CD8 T cell function regulated by T-bet
BM Sullivan et al.
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Perforin and the granule exocytosis cytotoxicity pathway
M Catalfamo et al.
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Sensitive and viable identification of antigen-specific CD8+T cells by a flow cytometric assay for degranulation
MR Betts et al.
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Characterization of the CD4+T cell response Epstein-Barr virus during primary and persistent infection
E Amyes et al.
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Primary immune responses to human CMV:: a critical role for IFN-γ-producing CD4+ T cells in protection against CMV disease
LE Gamadia et al.
BLOOD (2003)
The evolution of antigen-specific CD8(+) T cell responses after natural primary infection of humans with Epstein-Barr virus
MFC Callan
VIRAL IMMUNOLOGY (2003)
Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease
R Thimme et al.
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Prevalence and quantitation of species C adenovirus DNA in human mucosal lymphocytes
CT Garnett et al.
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MR Wills et al.
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V Appay et al.
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Distinct effects of T-bet in TH1 lineage commitment and IFN-γ production in CD4 and CD8 T cells
SJ Szabo et al.
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Memory T cells constitute a subset of the human CD8+CD45RA+ pool with distinct phenotypic and migratory characteristics
JM Faint et al.
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Virus-specific and bystander CD8+ T-cell proliferation in the acute and persistent phases of a gammaherpesvirus infection
GT Belz et al.
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Dissecting the host response to a γ-herpesvirus
PC Doherty et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2001)
Dynamics of T lymphocyte responses: Intermediates, effectors, and memory cells
A Lanzavecchia et al.
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Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8+ T lymphocytes in healthy seropositive donors
GMA Gillespie et al.
JOURNAL OF VIROLOGY (2000)
Cytolytic mechanisms and expression of activation-regulating receptors on effector-type CD8+CD45RA+CD27- human T cells
PA Baars et al.
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Changes in the composition of circulating CD8+ T cell subsets during acute Epstein-Barr and human immunodeficiency virus infections in humans
MTL Roos et al.
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A novel transcription factor, T-bet, directs Th1 lineage commitment
SJ Szabo et al.
CELL (2000)
Analysis of successful immune responses in persons infected with hepatitis C virus
F Lechner et al.
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