期刊
PLOS NEGLECTED TROPICAL DISEASES
卷 7, 期 10, 页码 -出版社
PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pntd.0002508
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资金
- GlaxoSmithKline (GSK)
- Merck Co.
- Mectizan Donation Program
- Bill & Melinda Gates Foundation
- Lions Clubs International Foundation SightFirst
- GSK
- WHO/World Bank African Programme for Onchocerciasis Control
In central Nigeria Anopheles mosquitoes transmit malaria and lymphatic filariasis (LF). The strategy used for interrupting LF transmission in this area is annual mass drug administration (MDA) with albendazole and ivermectin, but after 8 years of MDA, entomological evaluations in sentinel villages showed continued low-grade mosquito infection rates of 0.32%. After long-lasting insecticidal net (LLIN) distribution by the national malaria program in late 2010, however, we were no longer able to detect infected vectors over a 24-month period. This is evidence that LLINs are synergistic with MDA in interrupting LF transmission.
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