期刊
PLOS NEGLECTED TROPICAL DISEASES
卷 5, 期 9, 页码 -出版社
PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pntd.0001301
关键词
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资金
- Science and Technology Commission of Shanghai Municipality [10JC1406500]
- Open Foundation of State Key Laboratory of Veterinary Etiological Biology [SKLVEB2010KFKT011]
- Shanghai Municipal Education Commission
- Shanghai Education Development Foundation
- SMG
With the improvements in diagnostic techniques, Bartonella henselae (B. henselae) infection has recently been recognized to cause a widening spectrum of diseases. Cats are the natural reservoir hosts of B. henselae. The current study aims to investigate the prevalence of B. henselae infection in the cat populations in China. Polymerase chain reaction (PCR) and bacterial cultures confirm that 12.7% of the tested cats were positive for the infection. Old age and outdoor exposure were statistically associated with the infection. Multilocus sequence typing and eBURST analysis of the cat isolates collected in the present study show that 65.4% of the isolates belong to sequence type 1 (ST1). Three new STs (ST16-18) were identified in Midwestern China. These results may aid our understanding of the population structure of B. henselae in China and the relationship between human and cat strains in subsequent studies.
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