期刊
PLOS COMPUTATIONAL BIOLOGY
卷 10, 期 5, 页码 -出版社
PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pcbi.1003520
关键词
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It has recently been noted that the relative prevalence of the various kinds of epistasis varies along an adaptive walk. This has been explained as a result of mean regression in NK model fitness landscapes. Here we show that this phenomenon occurs quite generally in fitness landscapes. We propose a simple and general explanation for this phenomenon, confirming the role of mean regression. We provide support for this explanation with simulations, and discuss the empirical relevance of our findings.
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