期刊
NANOMATERIALS
卷 5, 期 4, 页码 1620-1637出版社
MDPI
DOI: 10.3390/nano5041620
关键词
nanotoxicology; metal oxide; quantitative structure activity relationship (QSAR); descriptor; toxicity mechanisms
类别
资金
- National Natural Science Foundation of China [81172697, 81302461, 81473003]
- National Important Project on Scientific Research of China [2011CB933404]
- Specialised Research Fund for the Doctoral Program of Higher Education [20130092120062]
Metal oxide nanomaterials are widely used in various areas; however, the divergent published toxicology data makes it difficult to determine whether there is a risk associated with exposure to metal oxide nanomaterials. The application of quantitative structure activity relationship (QSAR) modeling in metal oxide nanomaterials toxicity studies can reduce the need for time-consuming and resource-intensive nanotoxicity tests. The nanostructure and inorganic composition of metal oxide nanomaterials makes this approach different from classical QSAR study; this review lists and classifies some structural descriptors, such as size, cation charge, and band gap energy, in recent metal oxide nanomaterials quantitative nanostructure activity relationship (QNAR) studies and discusses the mechanism of metal oxide nanomaterials toxicity based on these descriptors and traditional nanotoxicity tests.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据