相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The Immunological Synapse: A Molecular Machine Controlling T Cell Activation
Arash Grakoui et al.
JOURNAL OF IMMUNOLOGY (2015)
Measuring diffusion and binding kinetics by contact area FRAP
Timothy P. Tolentino et al.
BIOPHYSICAL JOURNAL (2008)
Analysis of serial engagement and peptide-MHC transport in T cell receptor microclusters
Omer Dushek et al.
BIOPHYSICAL JOURNAL (2008)
Analysis of membrane-localized binding kinetics with FRAP
Omer Dushek et al.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2008)
Signal initiation in T-cell receptor microclusters
Maria-Cristina Seminario et al.
IMMUNOLOGICAL REVIEWS (2008)
Increased mobility of major histocompatibility complex I-peptide complexes decreases the sensitivity of antigen recognition
Jean-Manuel Segura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Stochastic effects and bistability in T cell receptor signaling
Tomasz Lipniacki et al.
JOURNAL OF THEORETICAL BIOLOGY (2008)
Quantitative challenges in understanding ligand discrimination by αβ T cells
Ofer Feinerman et al.
MOLECULAR IMMUNOLOGY (2008)
TCR Triggering by the pMHC Complex: Valency, Affinity, and Dynamics
Rajat Varma
SCIENCE SIGNALING (2008)
Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity
Zhengyu Ma et al.
PLOS BIOLOGY (2008)
Kinetics of MHC-CD8 interaction at the T cell membrane
Jun Huang et al.
JOURNAL OF IMMUNOLOGY (2007)
Kinetic evidence for a ligand-binding-induced conformational transition in the T cell receptor
Dmitry M. Gakamsky et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
CD8+ T cell activation is governed by TCR-Peptide/MHC affinity, not dissociation rate
Shaomin Tian et al.
JOURNAL OF IMMUNOLOGY (2007)
A role for self in T-cell activation
Michelle Krogsgaard et al.
SEMINARS IN IMMUNOLOGY (2007)
Molecular mechanisms involved in T cell receptor triggering
Kaushik Choudhuri et al.
SEMINARS IN IMMUNOLOGY (2007)
The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse
Saso Cemerski et al.
IMMUNITY (2007)
Analysis of two-dimensional dissociation constant of laterally mobile cell adhesion molecules
De-Min Zhu et al.
BIOPHYSICAL JOURNAL (2007)
Ligand detection and discrimination by spatial relocalization: A kinase-phosphatase segregation model of TCR activation
Nigel J. Burroughs et al.
BIOPHYSICAL JOURNAL (2006)
Altered peptide Ligands induce delayed CD8-T cell receptor interaction - a role for CD8 in distinguishing antigen quality
Pia P. Yachi et al.
IMMUNITY (2006)
The kinetic-segregation model: TCR triggering and beyond
Simon J. Davis et al.
NATURE IMMUNOLOGY (2006)
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster
Rajat Varma et al.
IMMUNITY (2006)
B cell ligand discrimination through a spreading and contraction response
SJ Fleire et al.
SCIENCE (2006)
Analysis of peptide/MHC-induced TCR downregulation
Clemens Utzny et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2006)
Incorporating diffusion in complex geometries into stochastic chemical kinetics simulations
SA Isaacson et al.
SIAM JOURNAL ON SCIENTIFIC COMPUTING (2006)
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76
T Yokosuka et al.
NATURE IMMUNOLOGY (2005)
Understanding specificity and sensitivity of T-cell recognition
AJT George et al.
TRENDS IN IMMUNOLOGY (2005)
Modeling T cell antigen discrimination based on feedback control of digital ERK responses
G Altan-Bonnet et al.
PLOS BIOLOGY (2005)
Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
G Campi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell
PA González et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity
M Krogsgaard et al.
NATURE (2005)
CD8 kinetically promotes ligand binding to the T-cell antigen receptor
DM Gakamsky et al.
BIOPHYSICAL JOURNAL (2005)
CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse
QJ Li et al.
NATURE IMMUNOLOGY (2004)
Feedback control of T-cell receptor activation
C Chan et al.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2004)
T cell killing does not require the formation of a stable mature immunological synapse
MA Purbhoo et al.
NATURE IMMUNOLOGY (2004)
Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation
PD Holler et al.
IMMUNITY (2003)
Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation
M Krogsgaard et al.
MOLECULAR CELL (2003)
Direct observation of ligand recognition by T cells
DJ Irvine et al.
NATURE (2002)
Activated TCRs remain marked for internalization after dissociation from pMHC
D Coombs et al.
NATURE IMMUNOLOGY (2002)
T cell receptor ligation induces the formation of dynamically regulated signaling assemblies
SC Bunnell et al.
JOURNAL OF CELL BIOLOGY (2002)
Costimulation and endogenous MHC ligands contribute to T cell recognition
C Wulfing et al.
NATURE IMMUNOLOGY (2002)
Cooperative enhancement of specificity in a lattice of T cell receptors
C Chan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
A reliable and safe T cell repertoire based on low-affinity T cell receptors
HA Van Den Berg et al.
JOURNAL OF THEORETICAL BIOLOGY (2001)
Efficient cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex
AM Kalergis et al.
NATURE IMMUNOLOGY (2001)
T cell receptor binding to a pMHCII ligand is kinetically distinct from and independent of CD4
Y Xiong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Calculations show substantial serial engagement of T cell receptors
C Wofsy et al.
BIOPHYSICAL JOURNAL (2001)
Differential clustering of CD4 and CD3ζ during T cell recognition
MF Krummel et al.
SCIENCE (2000)
Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition
PA van der Merwe et al.
SEMINARS IN IMMUNOLOGY (2000)