期刊
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY
卷 114, 期 5, 页码 S160-S166出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.oooo.2011.09.029
关键词
-
资金
- German Research Foundation DFG (Deutsche Forschungsgemeinschaft)
Objective. Algipore is a clinically established bone substitute. The present study evaluated the osseoconductive and resorptive characteristics of Algipore modified with collagen type I (ACI). Study Design. Three defects of 10 x 3 mm were set in the frontal bone of 10 adult female minipigs. One cavity was filled with commercially available Algipore, and the second with ACI. The third cavity was left unfilled and served as reference. After 4 months of healing, the animals were humanely killed. Bone formation and resorption characteristics of the substitutes were evaluated histomorphologically and histomorphometrically using Donath's sawing and grinding technique. Results. Neither material caused inflammatory reactions. Compared with controls, both substitutes showed significantly higher fractions of trabecular bone (control: 42.2%; Algipore: 58.7%, [P < .001]; ACI: 53.6%, [P = .013]). After 4 months, the remaining fraction of Algipore was 42.2% and the fraction of ACI was 47.9% (P = .016). Conclusions. The present study demonstrates that the modification of Algipore with collagen I does not show any benefits compared with pure Algipore in small calvarial bone defects in minipigs. (Oral Surg Oral Med Oral Pathol Oral Radiol 2012; 114(suppl 5)(suppl 5):S160-S166)
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据