期刊
NUTRITION & DIABETES
卷 3, 期 -, 页码 -出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nutd.2013.32
关键词
DASH; diet; cardiovascular risk factors; type 1 diabetes mellitus; type 2 diabetes mellitus; youth
资金
- Centers for Disease Control and Prevention [00097, DP-05-069, DP-10-001]
- National Institute of Diabetes and Digestive and Kidney Diseases
- Kaiser Permanente Southern California [U48/CCU919219, U01 DP000246, U18DP002714]
- University of Colorado Denver [U48/CCU819241-3, U01 DP000247, U18DP000247-06A1]
- Kuakini Medical Center [U58CCU919256, U01 DP000245]
- Children's Hospital Medical Center (Cincinnati) [U48/CCU519239, U01 DP000248, 1U18DP002709]
- University of North Carolina at Chapel Hill [U48/CCU419249, U01 DP000254, U18DP002708-01]
- University of Washington School of Medicine [U58/CCU019235-4, U01 DP000244, U18DP002710-01]
- Wake Forest University School of Medicine [U48/CCU919219, U01 DP000250, 200-2010-35171]
- General Clinical Research Center (GCRC) at the South Carolina Clinical & Translational Research (SCTR) Institute [UL1RR029882]
- General Clinical Research Center (GCRC) at the Medical University of South Carolina (NIH/NCRR) [UL1RR029882]
- Children's Hospital and Regional Medical Center [M01RR00037]
- Colorado Pediatric General Clinical Research Center [M01 RR00069]
- Barbara Davis Center at the University of Colorado at Denver [DERC NIH P30 DK57516]
- Institutional Clinical and Translational Science Award (CTSA), NIH/NCRR at the University of Cincinnati [1UL1RR026314-01]
Youth with diabetes are at an increased risk of cardiovascular disease (CVD). Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet has been shown to improve CVD risk. In this study, we evaluated whether changes in diet quality as characterized by DASH are associated with changes in CVD risk factors in youth with diabetes over time. Longitudinal mixed models were applied to data from 797 participants in the SEARCH for Diabetes in Youth Study representing three time points: baseline, 12- and 60-month follow-up. Data were restricted to youth whose diabetes was first diagnosed in 2002-2005. DASH-related adherence was poor and changed very little over time. However, an increase in DASH diet score was significantly associated with a decrease in HbA(1c) levels in youth with type 1 diabetes (beta = -0.20, P-value = 0.0063) and a decrease in systolic blood pressure among youth with type 2 diabetes (beta = -2.02, P-value = 0.0406). Improvements in dietary quality may be beneficial in youth with type 1 or type 2 diabetes. However, further work in larger groups of youth with type 1 and 2 diabetes is desirable.
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