Biocompatible Fluorescent Jelly Quantum Dots for Bioimaging

CdTe/CdSe quantum dots (QDs) embedded gelatin nanoparticles were synthesized via aqueous method. The morphology of the nanoparticles was characterized by transmission electron microscope (TEM) and the average size of QD/gelatin nanoparticles was 50 nm in size. The luminescent properties of these nanoparticles were studied by using fluorescence spectrophotometry and fluorescence microscopy. The nanoparticles was used for imaging cell lines such as GI-1, MCF 7, HUVEC, L929 and biocompatibility of nanoparticles was studied and found that the gelatin coated QDs are highly compatible even at higher concentrations of nanoparticles. Our results identify that biopolymer coated nanoparticles are expected to be ideal candidates for in vivo biological imaging studies.