期刊
JOURNAL OF SAUDI CHEMICAL SOCIETY
卷 16, 期 1, 页码 45-53出版社
ELSEVIER
DOI: 10.1016/j.jscs.2010.10.017
关键词
Michael addition; Benzothiazine; Benzodiazepine; PTC; Active methylene compounds
Michael addition reaction of 1,3-diphenyl-propenone 1a, e, and f with o-amino thiophenol in the presence of indium trichloride gave the benzothiazine derivatives 2a-c. Condensation of the compound 1a, e with o-phenylene diamine in triethylamine gave the benzodiazepine derivatives 3a-b. Cyclization of 1d with malononitrile in the presence of NaOR/EtOH gave the compound 4. Addition of thiobarbituric acid in triethylamin to 1a gave 5. Condensation of compound 1c with malononitrile in the presence ammonium acetate gave compound 6. 1,3-diphenyl-propenone 1a used as key starting chalcone to react with different active methylene reagents under phase-transfer catalysis condition gave compound 7-9. The structures of the prepared compounds were mainly confirmed on the basis of spectroscopic methods. (C) 2010 King Saud University. Production and hosting by Elsevier B. V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据