期刊
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
卷 -, 期 104, 页码 -出版社
JOURNAL OF VISUALIZED EXPERIMENTS
DOI: 10.3791/53124
关键词
Immunology; Issue 104; Drug development; antiviral activity; early viral entry; viral inactivation; viral attachment/binding; viral entry/fusion
资金
- Taipei Medical University Hospital [102TMU-TMUH-19]
- Ministry of Science and Technology of Taiwan [MOST103-2320-B-038-031-MY3]
Cell-based systems are useful for discovering antiviral agents. Dissecting the viral life cycle, particularly the early entry stages, allows a mechanistic approach to identify and evaluate antiviral agents that target specific steps of the viral entry. In this report, the methods of examining viral inactivation, viral attachment, and viral entry/fusion as antiviral assays for such purposes are described, using hepatitis C virus as a model. These assays should be useful for discovering novel antagonists/inhibitors to early viral entry and help expand the scope of candidate antiviral agents for further drug development.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据